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  1. Article

    Correction to: Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial

    The original article can be found onlineThe original article can be found online

    Hiroto Matsui, Shoichi Hazama, Masao Nakajima, Ming Xu in Cancer Immunology, Immunotherapy (2021)

  2. No Access

    Article

    Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial

    A proteomic analysis of hepatocellular carcinoma (HCC) has revealed that Heat Shock Protein 70 (HSP70) is among the cancer antigen proteins of HCC. Moreover, we confirmed that HSP70 was highly expressed in HCC...

    Hiroto Matsui Matsui, Shoichi Hazama, Masao Nakajima in Cancer Immunology, Immunotherapy (2021)

  3. No Access

    Article

    Antimicrobial prophylaxis for 1 day versus 3 days in liver cancer surgery: a randomized controlled non-inferiority trial

    This study compared the effectiveness of 1-day vs 3-days antibiotic regimen to prevent surgical site infection (SSI) in open liver resection.

    Tadatoshi Takayama, Osamu Aramaki, Taro Shibata, Masaaki Oka in Surgery Today (2019)

  4. No Access

    Article

    A phase II, multicenter, single-arm study of tri-weekly low-dose nanoparticle albumin-bound paclitaxel chemotherapy for patients with metastatic or recurrent breast cancer

    Nanoparticle albumin-bound (nab)-paclitaxel is a solvent-free formulation of paclitaxel that is bound to albumin and has demonstrated improved progression free survival in previous studies of breast cancer. Ho...

    Shigeru Yamamoto, Noriko Maeda, Yukiko Nagashima, Hidefumi Kubo, Yoko Sato in Breast Cancer (2017)

  5. No Access

    Article

    Breast sentinel lymph node navigation with three-dimensional computed tomography–lymphography: a 12-year study

    To evaluate the utility of three-dimensional (3D) computed tomography (CT)−lymphography (LG) breast sentinel lymph node navigation in our institute.

    Shigeru Yamamoto, Kazuyoshi Suga, Kazunari Maeda, Noriko Maeda in Breast Cancer (2016)

  6. Article

    Open Access

    Risk Factors and Managements of Bile Leakage After Hepatectomy

    The purpose of this study was to retrospectively determine the risk factors and evaluate the management of bile leakage.

    Kazuhiko Sakamoto, Takao Tamesa, Tokumitu Yukio in World Journal of Surgery (2016)

  7. Article

    Open Access

    Perioperative Microbiologic Monitoring of Sputum on Postoperative Day One as a Predictor of Pneumonia After Hepatectomy

    The purpose of this study was to retrospectively evaluate microbial examination of sputum on postoperative day one (POD1) and to determine risk factors for postoperative pneumonia (POP) after hepatectomy.

    Kazuhiko Sakamoto, Takao Tamesa, Yoshihiro Tokuhisa in Journal of Gastrointestinal Surgery (2015)

  8. No Access

    Article

    Dendritic cells transfected with heat-shock protein 70 messenger RNA for patients with hepatitis C virus-related hepatocellular carcinoma: a phase 1 dose escalation clinical trial

    We previously reported overexpression of heat-shock protein (HSP) 70 in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) using proteomic profiling and immunohistochemical staining (IHS). This su...

    Yoshinari Maeda, Kiyoshi Yoshimura, Hiroto Matsui in Cancer Immunology, Immunotherapy (2015)

  9. No Access

    Article

    Intraoperative dissemination during gastrectomy for gastric cancer associated with serosal invasion

    Free cancer cells shed from the serosal surface of gastric cancer result in peritoneal dissemination. The aim of this study was to clarify the extent of tumor cell implantation due to surgical manipulation dur...

    Yukio Tokumitsu, Shigefumi Yoshino, Michihisa Iida, Kiyoshi Yoshimura in Surgery Today (2015)

  10. Article

    Open Access

    Prognostic factors in patients with septic shock in digestive surgery who have undergone direct hemoperfusion with polymyxin B-immobilized fibers: a retrospective observational study

    Direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP) has been widely used for patients with septic shock around the world, but the prognostic factors have not been fully understood. We conducted a...

    Satoshi Matsukuma, Kazuhiko Sakamoto, Mitsuo Nishiyama in Journal of Intensive Care (2015)

  11. Article

    Open Access

    Relationship Between Cytokine Gene Polymorphisms and Risk of Postoperative Pneumonia with Esophageal Cancer

    We retrospectively evaluated the relationship between cytokine gene polymorphisms and development of postoperative pneumonia after esophagectomy.

    Kazuhiko Sakamoto, Masaaki Oka, Shigehumi Yoshino in Journal of Gastrointestinal Surgery (2014)

  12. No Access

    Article

    Impact of surgical site infection after colorectal surgery on hospital stay and medical expenditure in Japan

    To clarify the impact of surgical site infection (SSI) after colorectal surgery on the length of hospital stay and medical expenditure in Japan.

    Nobuichi Kashimura, Shinya Kusachi, Toshiro Konishi, Junzo Shimizu in Surgery Today (2012)

  13. No Access

    Article

    Prospective ultrasonographic prediction of sentinel lymph node metastasis by real-time virtual sonography constructed with three-dimensional computed tomography–lymphography in breast cancer patients

    Real-time virtual sonography (RVS) systems display virtual multiplanar reconstruction (MPR) images obtained from three-dimensional (3D) computed tomography (CT)–lymphography (LG), significantly improving preop...

    Shigeru Yamamoto, Noriko Maeda, Michiko Tamesa, Yukiko Nagashima in Breast Cancer (2012)

  14. No Access

    Article

    Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

    Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential a...

    Kiyoshi Yoshimura, Kelly Olino, Barish H. Edil, Richard D. Schulick in Surgery Today (2010)

  15. No Access

    Article

    The effect of adjuvant and neoadjuvant chemo(radio)therapy on survival in 1,679 resected pancreatic carcinoma cases in Japan: report of the national survey in the 34th annual meeting of Japanese Society of Pancreatic Surgery

    Pancreatic carcinoma causes more than 20,000 deaths every year in Japan. The role of (neo-) adjuvant chemotherapy for pancreatic carcinoma is still controversial.

    Naohiro Sata, Kentaro Kurashina, Hideo Nagai in Journal of Hepato-Biliary-Pancreatic Surge… (2009)

  16. No Access

    Article

    Improvement of early delayed gastric emptying in patients with Billroth I type of reconstruction after pylorus preserving pancreatoduodenectomy

    Early delayed gastric emptying (DGE) is the most common complication after pylorus-preserving pancreatoduodenectomy (PpPD). Recently, a vertical antecolic reconstruction for duodenojejunostomy was recommended ...

    Tomio Ueno, Motonari Takashima in Journal of Hepato-Biliary-Pancreatic Surge… (2009)

  17. No Access

    Article

    Involvement of c-myc-regulated genes in hepatocellular carcinoma related to genotype-C hepatitis B virus

    Purpose: The purpose of this study was to elucidate the molecular basis of hepatocellular carcinoma (HCC) caused by genotype-C hepatitis B virus (HBV). Methods: We compared molecular prof...

    Norio Iizuka, Ryouichi Tsunedomi in Journal of Cancer Research and Clinical On… (2006)

  18. No Access

    Article

    Current antibiotic prophylaxis in pancreatoduodenectomy in Japan

    The aim of this study was to investigate the current use of antibiotic prophylaxis (AP) in association with pancreatoduodenectomy (PD) in Japan, and to determine its surgical implications.

    Tomio Ueno, Koutaro Yamamoto, Toru Kawaoka in Journal of Hepato-Biliary-Pancreatic Surge… (2005)

  19. No Access

    Article

    Increased expression of MUC1 in advanced pancreatic cancer

    MUC1 is associated with tumor invasion and metastasis, and is expressed in pancreatic cancer with a high frequency. This study explored whether MUC1 expression affected the survival of patients with pancreatic...

    Yuji Hinoda, Yoshito Ikematsu, Michiko Horinochi, Shuji Sato in Journal of Gastroenterology (2003)

  20. No Access

    Article

    Differential gene expression in distinct virologic types of hepatocellular carcinoma: association with liver cirrhosis

    Using oligonucleotide microarray data of 45 hepatocellular carcinoma (HCC) samples, we evaluated gene expression in hepatitis B virus-positive and hepatitis C virus-positive HCCs (HBV- and HCV-HCCs) for an ass...

    Norio Iizuka, Masaaki Oka, Hisafumi Yamada-Okabe, Naohide Mori, Takao Tamesa in Oncogene (2003)

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