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  1. Article

    Open Access

    Evaluation of left ventricular filling pressure by echocardiography in patients with atrial fibrillation

    Echocardiography is widely used to evaluate left ventricular (LV) diastolic function in patients suspected of heart failure. For patients in sinus rhythm, a combination of several echocardiographic parameters ...

    Faraz H. Khan, Debbie Zhao, Jong-Won Ha, Sherif F. Nagueh in Echo Research & Practice (2024)

  2. Article

    Open Access

    Super-resolution 4D flow MRI to quantify aortic regurgitation using computational fluid dynamics and deep learning

    Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation (AR), a type of valvular heart disease. Metrics derived from blood flows are used to indicate AR onset and ...

    Derek Long, Cameron McMurdo, Edward Ferdian in The International Journal of Cardiovascula… (2023)

  3. No Access

    Article

    Left Ventricular Diastolic Myocardial Stiffness and End-Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis

    Understanding the aetiology of heart failure with preserved (HFpEF) and reduced (HFrEF) ejection fraction requires knowledge of biomechanical factors such as diastolic myocardial stiffness and stress. Cine CMR...

    Zhinuo J. Wang, Vicky Y. Wang in Journal of Cardiovascular Translational Re… (2018)

  4. No Access

    Chapter and Conference Paper

    Identification of Transversely Isotropic Properties from Magnetic Resonance Elastography Using the Optimised Virtual Fields Method

    Magnetic resonance elastography (MRE) has been used to estimate myocardial stiffness. However, inversion methods typically introduce unrealistic assumptions. The virtual fields method (VFM) has been proposed f...

    Renee Miller, Arunark Kolipaka in Functional Imaging and Modelling of the He… (2017)

  5. No Access

    Chapter and Conference Paper

    Three-Dimensional Quantification of Myocardial Collagen Morphology from Confocal Images

    The mechanical properties of myocardial tissue are primarily determined by the organisation of the collagen network. Quantitative measurements of collagen morphology can help to understand the structure-functi...

    Abdallah I. Hasaballa, Gregory B. Sands in Functional Imaging and Modelling of the He… (2017)

  6. Article

    Open Access

    Quantifying passive myocardial stiffness and wall stress in heart failure patients using personalized ventricular mechanics

    Zhinuo Jenny Wang, Vicky Y Wang in Journal of Cardiovascular Magnetic Resonan… (2016)

  7. No Access

    Chapter and Conference Paper

    Parameterisation of Multi-directional Diffusion Weighted Magnetic Resonance Images of the Heart

    This study presents a novel method for building parametric representations of myocardial microstructure of the left ventricle from multi-directional diffusion weighted magnetic resonance images (DWI). The dire...

    Bianca Freytag, Vicky Y. Wang in Statistical Atlases and Computational Mode… (2016)

  8. No Access

    Chapter and Conference Paper

    Determining Anisotropic Myocardial Stiffness from Magnetic Resonance Elastography: A Simulation Study

    Although magnetic resonance elastography (MRE) has the potential to non-invasively measure myocardial stiffness, myocardium is known to be anisotropic and it is not clear whether all material parameters can be...

    Renee Miller, Haodan Jiang, Ria Mazumder in Functional Imaging and Modeling of the Hea… (2015)

  9. No Access

    Chapter and Conference Paper

    Microstructural Remodelling and Mechanics of Hypertensive Heart Disease

    Changes in heart geometry and microstructural remodelling of myocardium are pathological processes that occur in heart failure (HF). The combination of effects often leads to compromised mechanical function of...

    Vicky Y. Wang, Alexander J. Wilson in Functional Imaging and Modeling of the Hea… (2015)

  10. No Access

    Chapter and Conference Paper

    Identifying Myocardial Mechanical Properties from MRI Using an Orthotropic Constitutive Model

    This paper presents a method to characterise the passive orthotropic and contractile properties of left ventricular (LV) myocardial tissue using MRI data of cardiac anatomy, structure and function. Personalise...

    Zhinuo J. Wang, Vicky Y. Wang, Sue-Mun Huang in Statistical Atlases and Computational Mode… (2015)

  11. No Access

    Chapter and Conference Paper

    Field-Based Parameterisation of Cardiac Muscle Structure from Diffusion Tensors

    This paper presents a robust method to directly construct parametric representations of myocardial structure using a left ventricular (LV) finite element model customised to diffusion tensors derived from card...

    Bianca Freytag, Vicky Y. Wang in Functional Imaging and Modeling of the Hea… (2015)

  12. Article

    Open Access

    Investigating heart failure mechanics using personalised human biophysical models

    Vicky Y Wang, Brett R Cowan in Journal of Cardiovascular Magnetic Resonan… (2013)

  13. No Access

    Chapter and Conference Paper

    Changes in In Vivo Myocardial Tissue Properties Due to Heart Failure

    A clinical image data driven mechanics analysis was used to quantify changes in tissue-specific passive and contractile material properties for groups of normal and HF patients. We have developed an automated ...

    Vicky Y. Wang, Alistair A. Young in Functional Imaging and Modeling of the Hea… (2013)

  14. No Access

    Chapter and Conference Paper

    Estimation of In Vivo Myocardial Fibre Strain Using an Architectural Atlas of the Human Heart

    We propose a methodology to estimate 3D+time maps of left ventricular (LV) fibre strain from human structural and dynamic MRI data. A biomechanical finite element model integrates fibre direction throughout th...

    Christopher Casta, Vicky Y. Wang in Functional Imaging and Modeling of the Hea… (2013)

  15. Article

    Open Access

    Interactive biventricular modeling tools for clinical cardiac image analysis

    Hoi-Ieng H Lam, Brett R Cowan, Martyn P Nash in Journal of Cardiovascular Magnetic Resonan… (2010)

  16. No Access

    Reference Work Entry In depth

    The Inverse Problem of Electrocardiography

    Andrew J. Pullan, Leo K. Cheng, Martyn P. Nash in Comprehensive Electrocardiology (2010)