![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessEvaluation of left ventricular filling pressure by echocardiography in patients with atrial fibrillation
Echocardiography is widely used to evaluate left ventricular (LV) diastolic function in patients suspected of heart failure. For patients in sinus rhythm, a combination of several echocardiographic parameters ...
-
Article
Open AccessSuper-resolution 4D flow MRI to quantify aortic regurgitation using computational fluid dynamics and deep learning
Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation (AR), a type of valvular heart disease. Metrics derived from blood flows are used to indicate AR onset and ...
-
Article
Left Ventricular Diastolic Myocardial Stiffness and End-Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis
Understanding the aetiology of heart failure with preserved (HFpEF) and reduced (HFrEF) ejection fraction requires knowledge of biomechanical factors such as diastolic myocardial stiffness and stress. Cine CMR...
-
Chapter and Conference Paper
Identification of Transversely Isotropic Properties from Magnetic Resonance Elastography Using the Optimised Virtual Fields Method
Magnetic resonance elastography (MRE) has been used to estimate myocardial stiffness. However, inversion methods typically introduce unrealistic assumptions. The virtual fields method (VFM) has been proposed f...
-
Chapter and Conference Paper
Three-Dimensional Quantification of Myocardial Collagen Morphology from Confocal Images
The mechanical properties of myocardial tissue are primarily determined by the organisation of the collagen network. Quantitative measurements of collagen morphology can help to understand the structure-functi...
-
Article
Open AccessQuantifying passive myocardial stiffness and wall stress in heart failure patients using personalized ventricular mechanics
-
Chapter and Conference Paper
Parameterisation of Multi-directional Diffusion Weighted Magnetic Resonance Images of the Heart
This study presents a novel method for building parametric representations of myocardial microstructure of the left ventricle from multi-directional diffusion weighted magnetic resonance images (DWI). The dire...
-
Chapter and Conference Paper
Determining Anisotropic Myocardial Stiffness from Magnetic Resonance Elastography: A Simulation Study
Although magnetic resonance elastography (MRE) has the potential to non-invasively measure myocardial stiffness, myocardium is known to be anisotropic and it is not clear whether all material parameters can be...
-
Chapter and Conference Paper
Microstructural Remodelling and Mechanics of Hypertensive Heart Disease
Changes in heart geometry and microstructural remodelling of myocardium are pathological processes that occur in heart failure (HF). The combination of effects often leads to compromised mechanical function of...
-
Chapter and Conference Paper
Identifying Myocardial Mechanical Properties from MRI Using an Orthotropic Constitutive Model
This paper presents a method to characterise the passive orthotropic and contractile properties of left ventricular (LV) myocardial tissue using MRI data of cardiac anatomy, structure and function. Personalise...
-
Chapter and Conference Paper
Field-Based Parameterisation of Cardiac Muscle Structure from Diffusion Tensors
This paper presents a robust method to directly construct parametric representations of myocardial structure using a left ventricular (LV) finite element model customised to diffusion tensors derived from card...
-
Article
Open AccessInvestigating heart failure mechanics using personalised human biophysical models
-
Chapter and Conference Paper
Changes in In Vivo Myocardial Tissue Properties Due to Heart Failure
A clinical image data driven mechanics analysis was used to quantify changes in tissue-specific passive and contractile material properties for groups of normal and HF patients. We have developed an automated ...
-
Chapter and Conference Paper
Estimation of In Vivo Myocardial Fibre Strain Using an Architectural Atlas of the Human Heart
We propose a methodology to estimate 3D+time maps of left ventricular (LV) fibre strain from human structural and dynamic MRI data. A biomechanical finite element model integrates fibre direction throughout th...
-
Article
Open AccessInteractive biventricular modeling tools for clinical cardiac image analysis
-
Reference Work Entry In depth
The Inverse Problem of Electrocardiography