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Chapter and Conference Paper
Map** Microcalcifications Between 2D Mammograms and 3D MRI Using a Biomechanical Model of the Breast
We propose a method to localise the 3D positions of microcalcifications found in X-ray mammograms using the 3D breast modelling framework of Chung et al. [1]. The accuracy of the method was first studied using...
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Chapter and Conference Paper
Method for Validating Breast Compression Models Using Normalised Cross-Correlation
To diagnose and manage breast cancer, X-ray mammography, ultrasound, and magnetic resonance (MR) imaging are used to image the breasts. In this chapter, we present a method for validating finite element (FE) b...
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Chapter and Conference Paper
Effects of Fetal Head Motion on Pelvic Floor Mechanics
We have developed a modelling framework to simulate vaginal delivery using individual-specific pelvic floor geometries derived from magnetic resonance images, which could potentially be used to study the effec...
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Chapter and Conference Paper
Map** Breast Cancer Between Clinical X-Ray and MR Images
Characterizing a breast lesion can involve comparing X-ray and magnetic resonance (MR) images of a patient’s breast. Tracking a lesion between these imaging modalities is nontrivial because of the different ty...
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Chapter and Conference Paper
A Quantitative Description of Pelvic Floor Muscle Fibre Organisation
The levator ani (LA) muscles play an important role in pelvic floor function. With the aid of computer models and mechanics simulations, the injury mechanism of LA muscles can be better understood to prevent p...
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Article
Anisotropic effects of the levator ani muscle during childbirth
Pelvic floor dysfunction and pelvic organ prolapse have been associated with damage to the levator ani (LA) muscle, but the exact mechanisms linking them remain unknown. It has been postulated that factors suc...
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Article
Estimating material parameters of a structurally based constitutive relation for skin mechanics
This paper presents a structurally based modeling framework to characterize the structure–function relation in skin tissues, based upon biaxial tensile experiments performed in vitro on porcine skin. Equi-axia...
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Chapter and Conference Paper
Effects of Levator Ani Muscle Morphology on the Mechanics of Vaginal Childbirth
Childbirth-induced trauma is one of the leading factors that cause pelvic floor (PF) muscle dysfunction. There is preliminary evidence to suggest that the morphology of the levator ani (LA) muscles influences ...
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Chapter and Conference Paper
Modelling Prone to Supine Breast Deformation Under Gravity Loading Using Heterogeneous Finite Element Models
Biomechanical models of the breast can be used to co-locate information between the various medical images to identify tumour locations, while also providing the ability to predict their locations during surgi...
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Chapter
Patient-Specific Modeling of Breast Biomechanics with Applications to Breast Cancer Detection and Treatment
There are many challenges clinicians are faced with when diagnosing and treating breast cancer. Biomechanical modeling of the breast is a field of research that aims to assist clinicians by providing a physics...
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Chapter and Conference Paper
Identification of Tongue Muscle Fibre Group Contraction from MR Images
The tongue is made up of a collection of interwoven families of muscle fibres, but little is known about the function of each of these muscle groups during physiological motions of the tongue. Magnetic resonan...
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Article
Model-based identification of motion sensor placement for tracking retraction and elongation of the tongue
Electromagnetic articulography (EMA) is designed to track facial and tongue movements. In practice, the EMA sensors for tracking the movement of the tongue’s surface are placed heuristically. No recommendation...
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Chapter and Conference Paper
Automatic Landmark Detection Using Statistical Shape Modelling and Template Matching
We propose a new methodology for automated landmark detection for breast MR images that combines statistical shape modelling and template matching into a single framework. The method trains a statistical shape...
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Chapter and Conference Paper
Robust Landmark Identification for Generating Subject Specific Models for Biomechanics
We propose a robust and accurate method for automatic landmark identification for torso MR images. The method combines cross-correlation and statistical models into a single framework. Principal component anal...
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Chapter and Conference Paper
Registration of Prone and Supine Breast MRI for Breast Cancer Treatment Planning
This study aimed to determine the accuracy to which prone and supine MRI can be registered using biomechanical models, to help clinicians with pre-operative breast cancer treatment planning. A framework was de...
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Chapter and Conference Paper
Abusive Head Trauma: Develo** a Computational Adult Head Model to Predict Brain Deformations under Mild Accelerations
Abusive head trauma, previously termed “shaken baby syndrome”, refers to head injuries inflicted on young infants by their caregivers. There is currently a lack of scientific evidence around the causes of thes...
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Chapter and Conference Paper
Subpixel Measurement of Living Skin Deformation Using Intrinsic Features
Accurate measurement of skin deformation is essential to study and understand its behaviour under mechanical load. Digital image correlation (DIC) techniques are commonly used for in-vivo subpixel measurements...
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Article
Modelling Cardiac Tissue Growth and Remodelling
Cardiac growth and remodelling are key phenomena influencing the physiological performance of the heart and progression of various cardiac diseases. Our basic knowledge of the characteristics of cardiac growth...
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Chapter and Conference Paper
Image-Based Biomechanical Modelling of Heart Failure
Effective diagnosis and treatment of cardiovascular disease is hampered by a lack of knowledge of the underlying pathophysiological mechanisms on a patient-specific basis. Biomechanical factors, such as intrin...
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Chapter and Conference Paper
Quantifying Carotid Pulse Waveforms Using Subpixel Image Registration
Cardiovascular diseases are a common cause of death. Symptoms of cardiovascular disease often arise at a stage of the disease where treatments are ineffective. Hence, methods that can help early diagnosis of h...