Computational Biomechanics for Medicine
Towards Automation and Robustness of Computations in the Clinic
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Martyn P. Nash
Engineering
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Chapter and Conference Paper
Workflow for Generating Personalised Anatomical Models of the Skeleton and the Skin Surface of the Upper Torso
Breast cancer is the leading cause of cancer-related death in women worldwide. Diagnostic imaging such as 3D magnetic resonance imaging (MRI) is acquired with patients positioned in the prone orientation with ...
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Chapter and Conference Paper
Rapid Prediction of Breast Biomechanics Under Gravity Loading Using Surrogate Machine Learning Models
Identifying and localising breast tumours is challenging due to differing patient positions between clinical examination and treatment procedures. Individual-specific, physics-driven of the breast can help c...
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Book and Conference Proceedings
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Chapter and Conference Paper
Assessing Fibre Reorientation in Soft Tissues with Simultaneous Mueller Matrix Imaging and Mechanical Testing
The implantation of bioprosthetic heart valves constructed from membranes, such as bovine pericardium, porcine pericardium, and porcine heart valves, is a common method of treatment for valvular heart diseas...
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Chapter and Conference Paper
Measuring Three-Dimensional Surface Deformations of Skin Using a Stereoscopic System and Intrinsic Features
Measurement of three-dimensional (3D) surface deformations is an important step in characterising mechanical properties and develo** computational models . Compared to two-dimensional , the ability to acqu...
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Book and Conference Proceedings
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Chapter and Conference Paper
Removing Drift from Carotid Arterial Pulse Waveforms: A Comparison of Motion Correction and High-Pass Filtering
Non-invasive methods for estimating carotid artery (CA) pressure waveforms have been recently developed as a tool to detect heart abnormalities. Among non-invasive techniques, camera-based methods have the adv...
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Article
Surface deformation tracking and modelling of soft materials
Many computer vision algorithms have been presented to track surface deformations, but few have provided a direct comparison of measurements with other stereoscopic approaches and physics-based models. We have...
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Chapter and Conference Paper
Image-Based Biomechanical Modelling of Heart Failure
Effective diagnosis and treatment of cardiovascular disease is hampered by a lack of knowledge of the underlying pathophysiological mechanisms on a patient-specific basis. Biomechanical factors, such as intrin...
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Chapter and Conference Paper
Quantifying Carotid Pulse Waveforms Using Subpixel Image Registration
Cardiovascular diseases are a common cause of death. Symptoms of cardiovascular disease often arise at a stage of the disease where treatments are ineffective. Hence, methods that can help early diagnosis of h...
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Article
Modelling Cardiac Tissue Growth and Remodelling
Cardiac growth and remodelling are key phenomena influencing the physiological performance of the heart and progression of various cardiac diseases. Our basic knowledge of the characteristics of cardiac growth...
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Chapter and Conference Paper
Registration of Prone and Supine Breast MRI for Breast Cancer Treatment Planning
This study aimed to determine the accuracy to which prone and supine MRI can be registered using biomechanical models, to help clinicians with pre-operative breast cancer treatment planning. A framework was de...
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Chapter and Conference Paper
Abusive Head Trauma: Develo** a Computational Adult Head Model to Predict Brain Deformations under Mild Accelerations
Abusive head trauma, previously termed “shaken baby syndrome”, refers to head injuries inflicted on young infants by their caregivers. There is currently a lack of scientific evidence around the causes of thes...
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Chapter and Conference Paper
Subpixel Measurement of Living Skin Deformation Using Intrinsic Features
Accurate measurement of skin deformation is essential to study and understand its behaviour under mechanical load. Digital image correlation (DIC) techniques are commonly used for in-vivo subpixel measurements...
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Chapter and Conference Paper
Robust Landmark Identification for Generating Subject Specific Models for Biomechanics
We propose a robust and accurate method for automatic landmark identification for torso MR images. The method combines cross-correlation and statistical models into a single framework. Principal component anal...
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Chapter and Conference Paper
Automatic Landmark Detection Using Statistical Shape Modelling and Template Matching
We propose a new methodology for automated landmark detection for breast MR images that combines statistical shape modelling and template matching into a single framework. The method trains a statistical shape...
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Article
Model-based identification of motion sensor placement for tracking retraction and elongation of the tongue
Electromagnetic articulography (EMA) is designed to track facial and tongue movements. In practice, the EMA sensors for tracking the movement of the tongue’s surface are placed heuristically. No recommendation...
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Chapter and Conference Paper
Identification of Tongue Muscle Fibre Group Contraction from MR Images
The tongue is made up of a collection of interwoven families of muscle fibres, but little is known about the function of each of these muscle groups during physiological motions of the tongue. Magnetic resonan...
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Chapter and Conference Paper
Effects of Levator Ani Muscle Morphology on the Mechanics of Vaginal Childbirth
Childbirth-induced trauma is one of the leading factors that cause pelvic floor (PF) muscle dysfunction. There is preliminary evidence to suggest that the morphology of the levator ani (LA) muscles influences ...
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Chapter and Conference Paper
Modelling Prone to Supine Breast Deformation Under Gravity Loading Using Heterogeneous Finite Element Models
Biomechanical models of the breast can be used to co-locate information between the various medical images to identify tumour locations, while also providing the ability to predict their locations during surgi...
