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Article
Open AccessCorrection to: Brain MRI findings and their association with visual impairment in young adolescents born very preterm
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Article
Open AccessAtrioventricular Area Difference Aids Diastolic Filling in Patients with Repaired Tetralogy of Fallot
A hydraulic force aids diastolic filling of the left ventricle (LV) and is proportional to the difference in short-axis area between the left ventricle and atrium; the atrioventricular area difference (AVAD). ...
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Article
Open AccessBrain MRI findings and their association with visual impairment in young adolescents born very preterm
Very preterm birth increases risk for neonatal white matter injury, but there is limited data on to what extent this persists into adolescence and how this relates to ophthalmological outcomes. The aim of this...
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Article
Open AccessCorrection: Right ventricular longitudinal function is linked to left ventricular filling pressure in patients with repaired tetralogy of Fallot
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Article
Open AccessExposure to nonanoic acid alters small intestinal neuroendocrine tumor phenotype
Small intestinal neuroendocrine tumors (SI-NET) are highly differentiated and genetically stable malignant tumors, yet they often present with advanced metastatic spread at the time of diagnosis. In contrast t...
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Article
Open AccessCorrection: Content and strength of conflict of interest policies at scandinavian medical schools: a cross sectional study
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Article
Open AccessRight ventricular longitudinal function is linked to left ventricular filling pressure in patients with repaired tetralogy of fallot
Experimental data on pulmonary regurgitation has linked right ventricular longitudinal function to left ventricular filling pressure in animals with induced and treated pulmonary regurgitation but this relatio...
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Article
Open AccessContent and strength of conflict of interest policies at Scandinavian medical schools: a cross sectional study
Concerns around staffs’ and students’ interactions with commercial entities, for example drug companies, have led several North American medical schools to implement conflict of interest (COI) policies. Howeve...
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Article
Open AccessInhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer
There is an urgent need for new treatment options in metastatic drug-resistant prostate cancer. Combining immunotherapy with other targeted therapies may be an effective strategy for advanced prostate cancer. ...
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Article
Open AccessGaliellalactone inhibits the STAT3/AR signaling axis and suppresses Enzalutamide-resistant Prostate Cancer
Most prostate cancer patients will progress to a castration-resistant state (CRPC) after androgen ablation therapy and despite the development of new potent anti-androgens, like enzalutamide (ENZ), which prolo...
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Article
Open AccessA minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis
The role of B-lymphocytes in solid tumours is unclear. Tumour biology studies have implied both anti- and pro-tumoural effects and prognostic studies have mainly linked B-cells to increased survival. This stud...
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Article
Open AccessThe GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization
In the cell, γ-tubulin establishes a cellular network of threads named the γ-string meshwork. However, the functions of this meshwork remain to be determined. We investigated the traits of the meshwork and sho...
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Article
Open AccessPerivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma
Renal cell carcinoma (RCC) is a highly vascularised tumour, where anti-angiogenic treatment with multi-tyrosine-kinase-inhibitor, is used for first-line treatment of metastatic disease. Variations in vascular ...
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Article
Open AccessAnalysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis
The complement system has been implicated in pathogenesis of systemic sclerosis (SSc). The goal of the present study was to evaluate improved complement biomarkers in SSc.
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Article
Open AccessSimultaneous targeted activation of Notch1 and Vhl-disruption in the kidney proximal epithelial tubular cells in mice
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer, representing approximately 75% of all renal neoplasms. ccRCC is known to be strongly associated with silencing of the von Hippe...
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Article
Open AccessTRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex
Metastasis is a significant health issue. The standard mode of care is combination of chemotherapy and targeted therapeutics but the 5-year survival rate remains low. New/better drug targets that can improve o...
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Article
Open AccessEarly diagnostic value of Bcl-3 localization in colorectal cancer
B-cell leukemia 3 (Bcl-3) is a member of the inhibitor of κB family, which regulates a wide range of biological processes by functioning as a transcriptional activator or as a repressor of target genes. Elevat...
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Article
Open AccessEvaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with 177Lu-octreotate
The kidneys are regarded as one of the main dose-limiting organs in the treatment of neuroendocrine tumours with 177Lu-[DOTA0, Tyr3]-octreotate (177Lu-octreotate), despite the successful use of kidney uptake bloc...
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Chapter and Conference Paper
Tutoring Robots
This project explores a novel experimental setup towards building spoken, multi-modally rich, and human-like multiparty tutoring agent. A setup is developed and a corpus is collected that targets the developme...
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Article
Open AccessAssociation between the PTPN22+1858 C/T polymorphism and psoriatic arthritis
The purpose of the present study was to investigate the frequency of the PTPN22 +1858 C/T single nucleotide polymorphism (SNP) (rs 2476601), previously shown to be associated with several autoimmune diseases, in ...