4 Result(s)
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Martin Ingelsson
Behavioral Sciences
Medicine/Public Health, general
Neurosciences
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Article
Lack of fibrillar amyloid plaques but hypometabolism and astrogliosis in autosomal dominant variant AßPParc Alzheimer’s disease
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Article
Open AccessAstroglial tracer BU99008 detects multiple binding sites in Alzheimer’s disease brain
With reactive astrogliosis being established as one of the hallmarks of Alzheimer’s disease (AD), there is high interest in develo** novel positron emission tomography (PET) tracers to detect early astrocyte...
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Article
Open AccessAmyloid, tau, and astrocyte pathology in autosomal-dominant Alzheimer’s disease variants: AβPParc and PSEN1DE9
Autosomal-dominant Alzheimer’s disease (ADAD) may be associated with atypical amyloid beta deposits in the brain. In vivo amyloid imaging using 11C-Pittsburgh compound B (PiB) tracer has shown differences in bind...
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Article
Open AccessTransethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease
Rare coding variants in TREM2, PLCG2, and ABI3 were recently associated with the susceptibility to Alzheimer’s disease (AD) in Caucasians. Frequencies and AD-associated effects of variants differ across ethniciti...
