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  1. No Access

    Article

    Systemic high-dose intravenous methotrexate for central nervous system metastases

    Andrew B. Lassman, Lauren E. Abrey, Gaurav D. Shah… in Journal of Neuro-Oncology (2006)

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    Article

    Systemic high-dose intravenous methotrexate for central nervous system metastases

    Treatment options for patients with recurrent central nervous system (CNS) metastases are limited. Rapid infusion of high-dose intravenous methotrexate (HD IV MTX) penetrates the blood-brain barrier (BBB) and ...

    Andrew B. Lassman, Lauren E. Abrey, Gaurav G. Shah… in Journal of Neuro-Oncology (2006)

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    Article

    Necrotizing vasculopathy of the CNS: case report

    A 62-year-old man with progressive cerebellar and brainstem dysfunction had gadolinium-enhancing lesions in basal ganglia and occipital lobe on MRI suggestive of primary CNS lymphoma (PCNSL). The patient, who ...

    Martin Begemann, George Krol, Marc K. Rosenblum… in Journal of Neuro-Oncology (2005)

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    Article

    Leptomeningeal metastases from recurrent squamous cell cancer of the skin

    We report two patients with leptomeningeal metastases from squamous cell cancer of the skin. In one patient cauda equina metastases appeared 6 years after initial presentation; the tumor from radical neck diss...

    Martin Begemann, Marc K. Rosenblum, John Loh, Dennis Kraus… in Journal of Neuro-Oncology (2003)

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    Article

    Primary Leptomeningeal Primitive Neuroectodermal Tumor

    Leptomeningeal metastases are a common complication of medulloblastomas and other primitive neuroectodermal tumors (PNETs). Much rarer are PNETs apparently arising in the leptomeninges. An 8-year-old boy prese...

    Martin Begemann, David Lyden, Marc K. Rosenblum, Eric Lis… in Journal of Neuro-Oncology (2003)

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    Article

    Genomic changes in glioblastoma cell lines detected by comparative genomic hybridization

    Comparative genomic hybridization serves as a screening test for regions of copy number changes in tumor genomes. We have applied the technique to map DNA gains and losses in 5 cell lines derived from glioblas...

    Vijayanagaram S. Venkatraj, Martin Begemann, Antonio Sobrino… in Journal of Neuro-Oncology (1998)