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    Biophysical Methods for Identifying Fragment-Based Inhibitors of Protein-Protein Interactions

    Fragment-based lead discovery complements high-throughput screening and computer-aided drug design for the discovery of small-molecule inhibitors of protein-protein interactions. Fragments are molecules with m...

    Samuel J. Pfaff, Michael S. Chimenti, Mark J. S. Kelly… in Protein-Protein Interactions (2015)