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  1. Article

    Open Access

    A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells

    Innate Lymphoid Cells (ILCs) are immune cells typically found on mucosal surfaces and in secondary lymphoid organs where they regulate the immune response to pathogens. Despite their key role in the immune res...

    Margaret H. O’Connor, Roshell Muir, Marita Chakhtoura in Communications Biology (2021)

  2. Article

    Open Access

    Drug perturbation gene set enrichment analysis (dpGSEA): a new transcriptomic drug screening approach

    In this study, we demonstrate that our modified Gene Set Enrichment Analysis (GSEA) method, drug perturbation GSEA (dpGSEA), can detect phenotypically relevant drug targets through a unique transcriptomic enri...

    Mike Fang, Brian Richardson, Cheryl M. Cameron, Jean-Eudes Dazard in BMC Bioinformatics (2021)