7 Result(s)
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Article
Open AccessHigher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling
Observational studies suggest interconnections between thyroid status, metabolism, and risk of coronary artery disease (CAD), but causality remains to be proven. The present study aimed to investigate the pote...
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Open AccessInvestigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses
Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk...
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Article
Open AccessChildhood overweight and obesity and the risk of depression across the lifespan
Obesity has been longitudinally associated with depression but only few studies take a life course approach. This longitudinal study investigates whether being overweight or obese at age 8 and 13 years is asso...
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Article
Open AccessMajor depression and enhanced molecular senescence abnormalities in young and middle-aged adults
Recent evidence suggests a significant overlap in biological changes between major depression and aging across the lifespan. We aim to evaluate the impact of a major depressive episode on the Senescence-Associate...
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Article
Open AccessThe relation between obesity and depressed mood in a multi-ethnic population. The HELIUS study
To examine the association between obesity and depressed mood in a large multi-ethnic population and check for consistency in this association across six ethnic groups.
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Open AccessPrevention of depression through nutritional strategies in high-risk persons: rationale and design of the MooDFOOD prevention trial
Obesity and depression are two prevalent conditions that are costly to individuals and society. The bidirectional association of obesity with depression, in which unhealthy dietary patterns may play an importa...
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Article
Open AccessDiabetes MILES – The Netherlands: rationale, design and sample characteristics of a national survey examining the psychosocial aspects of living with diabetes in Dutch adults
As the number of people with diabetes is increasing rapidly worldwide, a more thorough understanding of the psychosocial aspects of living with this condition has become an important health care priority. Whil...
