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  1. No Access

    Article

    Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock

    Blunt chest (thoracic) trauma (TxT) and hemorrhagic shock (HS)-induced local and systemic inflammation with increased neutrophil activity often result in an impaired organ function. Next to increasing the trau...

    Niklas Franz, Scott Dieteren, Kernt Köhler, Katharina Mörs, Ramona Sturm… in Inflammation (2019)

  2. Article

    Open Access

    The immune response after fracture trauma is different in old compared to young patients

    Despite significant medical progress and improved treatment, surgical procedures of proximal femur fractures in older patients are still associated with a high postoperative complication and mortality rate. Re...

    Helen Vester, Markus S Huber-Lang, Qerim Kida, Alexander Scola… in Immunity & Ageing (2014)

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  3. No Access

    Chapter

    Granzyme B: A New Crossroad of Complement and Apoptosis

    In response to severe tissue trauma, several “molecular danger” sensing and signaling pathways are activated, especially the complement and the apoptosis cascade. Although possible crossroads between both syst...

    Mario Perl, Stephanie Denk, Miriam Kalbitz… in Current Topics in Innate Immunity II (2012)

  4. Article

    Open Access

    Epithelial Cell Apoptosis and Neutrophil Recruitment in Acute Lung Injury—A Unifying Hypothesis? What We Have Learned from Small Interfering RNAs

    In spite of protective ventilatory strategies, Acute Lung Injury (ALI) remains associated with high morbidity and mortality. One reason for the lack of therapeutic options might be that ALI is a co-morbid even...

    Mario Perl, Joanne Lomas-Neira, Chun-Shiang Chung, Alfred Ayala in Molecular Medicine (2008)

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