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    Open Access

    Tumor mutational burden assessment and standardized bioinformatics approach using custom NGS panels in clinical routine

    High tumor mutational burden (TMB) was reported to predict the efficacy of immune checkpoint inhibitors (ICIs). Pembrolizumab, an anti-PD-1, received FDA-approval for the treatment of unresectable/metastatic t...

    Célia Dupain, Tom Gutman, Elodie Girard, Choumouss Kamoun, Grégoire Marret… in BMC Biology (2024)

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