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  1. Article

    Open Access

    The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

    Dissemination of high-grade serous ovarian cancer (HG-SOC) in the omentum and intercalation into a mesothelial cell (MC) monolayer depends on functional α5β1 integrin (Intα5β1) activity. Although the binding o...

    Ilenia Masi, Flavia Ottavi, Danila Del Rio, Valentina Caprara… in Cell Death & Disease (2023)

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  2. Article

    Open Access

    Preclinical models of epithelial ovarian cancer: practical considerations and challenges for a meaningful application

    Despite many improvements in ovarian cancer diagnosis and treatment, until now, conventional chemotherapy and new biological drugs have not been shown to cure the disease, and the overall prognosis remains poo...

    Alessandra Ciucci, Marianna Buttarelli… in Cellular and Molecular Life Sciences (2022)

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  3. Article

    Open Access

    Stat1 confers sensitivity to radiation in cervical cancer cells by controlling Parp1 levels: a new perspective for Parp1 inhibition

    Cervical cancer (CC) is the fourth most common cause of cancer-related death in women. According to international guidelines, a standard treatment for locally advanced cervical cancer (LACC) consists of exclus...

    Giuseppina Raspaglio, Marianna Buttarelli, Flavia Filippetti… in Cell Death & Disease (2021)

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