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Article

Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B

Cancer stem cells (CSCs) are a subpopulation of cancer cells endowed with high tumorigenic, chemoresistant and metastatic potential. Nongenetic mechanisms of acquired resistance are increasingly being discover...

Martina Musella, Andrea Guarracino, Nicoletta Manduca, Claudia Galassi… in Nature Immunology (2022)