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Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

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  1. Article

    Open Access

    Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient

    Adoptive T-cell based immunotherapies constitute a promising approach to treat cancer, however, a major problem is to obtain effective and long-lasting anti-tumor responses. Lack of response may be due to insu...

    Imran Siddiqui, Marco Erreni, Mandy van Brakel… in Journal for ImmunoTherapy of Cancer (2016)

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  2. Article

    Open Access

    Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism

    Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays...

    Mara Mazzoni, Giuseppe Mauro, Marco Erreni… in Journal of Experimental & Clinical Cancer … (2019)

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