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  1. Article

    Open Access

    How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?

    Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, “Biology in Space and Analogue...

    Craig R. G. Willis, Marco Calvaruso, Debora Angeloni, Sarah Baatout in npj Microgravity (2024)

  2. Article

    Open Access

    How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

    Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gr...

    Trent Davis, Kevin Tabury, Shouan Zhu, Debora Angeloni, Sarah Baatout in npj Microgravity (2024)

  3. Article

    Open Access

    How do gravity alterations affect animal and human systems at a cellular/tissue level?

    The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gra...

    Francesca Cialdai, Austin M. Brown, Cory W. Baumann, Debora Angeloni in npj Microgravity (2023)

  4. Article

    Open Access

    Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model

    Despite aggressive therapeutic regimens, glioblastoma (GBM) represents a deadly brain tumor with significant aggressiveness, radioresistance and chemoresistance, leading to dismal prognosis. Hypoxic microenvir...

    Francesco Paolo Cammarata, Filippo Torrisi, Nunzio Vicario in Communications Biology (2023)