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  1. Article

    Open Access

    Hemophagocytic lymphohistiocytosis—how common and how severe is it as a complication of malaria? Retrospective case series and review of the literature

    Infection-associated secondary hemophagocytic lymphohistiocytosis (sHLH) is a potentially life-threatening hyperinflammatory condition caused by various infectious diseases. Malaria has rarely been described a...

    Hans Martin Orth, Dorothea Wiemer, Sophie Schneitler, Andreas Schönfeld in Infection (2024)

  2. Article

    Open Access

    Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

    Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used ...

    Stefan J. Frohberger, Jesuthas Ajendra, Jayagopi Surendar in Parasites & Vectors (2019)

  3. Article

    Open Access

    Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses

    One of the most advantageous research aspects of the murine model of filariasis, Litomosoides sigmodontis, is the availability of mouse strains with varying susceptibility to the nematode infection. In C57BL/6 mi...

    Laura E. Layland, Jesuthas Ajendra, Manuel Ritter, Anna Wiszniewsky in Parasites & Vectors (2015)