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Open AccessThe roles of neutrophils in non-tuberculous mycobacterial pulmonary disease
Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) is an increasingly recognised global health issue. Studies have suggested that neutrophils may play an important role in controlling NTM infection and c...
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Tuberculosis in People Living with HIV
Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection occurs throughout the world, and remains a significant challenge to TB control. Both HIV and TB cause immune dysregulation that can result .....
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Post-Tuberculosis Infections and Chronic Lung Disease
There is an increased awareness of the long-term physical, psychological and socioeconomic consequences that can follow apparently successful treatment for tuberculosis (TB). In this chapter, we describe the h.....
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Article
Open AccessAnticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions...
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Article
Open AccessHigh mortality in patients with Mycobacterium avium complex lung disease: a systematic review
The incidence of nontuberculous mycobacterial (NTM) pulmonary disease caused by Mycobacterium avium complex (MAC) in apparently immune-competent people is increasing worldwide. We performed a systematic review of...
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Open AccessVariation in C - reactive protein response according to host and mycobacterial characteristics in active tuberculosis
The C - reactive protein (CRP) response is often measured in patients with active tuberculosis (TB) yet little is known about its relationship to clinical features in TB, or whether responses differ between et...
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Article
Open AccessPulmonary Mycobacterium avium-intracellulare is the main driver of the rise in non-tuberculous mycobacteria incidence in England, Wales and Northern Ireland, 2007–2012
The incidence of non-tuberculous mycobacteria (NTM) isolation from humans is increasing worldwide. In England, Wales and Northern Ireland (EW&NI) the reported rate of NTM more than doubled between 1996 and 200...