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Article
Open AccessThe roles of neutrophils in non-tuberculous mycobacterial pulmonary disease
Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) is an increasingly recognised global health issue. Studies have suggested that neutrophils may play an important role in controlling NTM infection and c...
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Article
Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings
The risk of tuberculosis (TB) is variable among individuals with latent Mycobacterium tuberculosis infection (LTBI), but validated estimates of personalized risk are lacking. In pooled data from 18 systematically...
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Article
Open AccessAnticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions...
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Chapter
Global Epidemiology of NTM Disease (Except Northern America)
This chapter summarizes the epidemiology of NTM isolations and NTM disease worldwide. Understanding of the global epidemiology of NTM disease is evolving due to heterogeneity of NTM isolation from continent to...
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Article
Open AccessHigh mortality in patients with Mycobacterium avium complex lung disease: a systematic review
The incidence of nontuberculous mycobacterial (NTM) pulmonary disease caused by Mycobacterium avium complex (MAC) in apparently immune-competent people is increasing worldwide. We performed a systematic review of...
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Article
Open AccessResilience and Physical and Mental Well-Being in Adults with and Without HIV
Resilience has been related to improved physical and mental health, and is thought to improve with age. No studies have explored the relationship between resilience, ageing with HIV, and well-being. A cross se...
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Article
Open AccessVariation in C - reactive protein response according to host and mycobacterial characteristics in active tuberculosis
The C - reactive protein (CRP) response is often measured in patients with active tuberculosis (TB) yet little is known about its relationship to clinical features in TB, or whether responses differ between et...
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Article
Open AccessPulmonary Mycobacterium avium-intracellulare is the main driver of the rise in non-tuberculous mycobacteria incidence in England, Wales and Northern Ireland, 2007–2012
The incidence of non-tuberculous mycobacteria (NTM) isolation from humans is increasing worldwide. In England, Wales and Northern Ireland (EW&NI) the reported rate of NTM more than doubled between 1996 and 200...
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Article
Community-Acquired Pneumonia in HIV-Infected Individuals
Community-acquired pneumonia continues to be an important complication of HIV infection. Rates of pneumonia decrease with the use of antiretroviral therapy but continue to be higher than in HIV uninfected indi...
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Chapter
The Management of Multiple Drug-Resistant Tuberculosis
Tuberculosis (TB) will not go away. The decline that has occurred in rates in high-income countries because of chemotherapy (1) has now been reversed; TB remains the leading cause of death worldwide. Between 1998...