8 Result(s)
within
María T. Zarrabeitia
Medical Law
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Article
Indel analysis by droplet digital PCR: a sensitive method for DNA mixture detection and chimerism analysis
Several methods have been developed to determinate genetic profiles from a mixed samples and chimerism analysis in transplanted patients. The aim of this study was to explore the effectiveness of using the dro...
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Article
Development and validation of a multiplex reaction analyzing eight miniSTRs of the X chromosome for identity and kinship testing with degraded DNA
We report the development of an effective system for analyzing X chromosome-linked mini short tandem repeat loci with reduced-size amplicons (less than 220 bp), useful for analyzing highly degraded DNA samples...
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Article
miRNA analysis in vitreous humor to determine the time of death: a proof-of-concept pilot study
We hypothesized that miRNAs present in vitreous humor could be a sort of “biological black box,” storing information about physiological and environmental circumstances at death. As a proof of concept, we anal...
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Article
Forensic efficiency of microsatellites and single nucleotide polymorphisms on the X chromosome
Polymorphisms located on the X chromosome are being increasingly used in forensic studies. However, they have not been studied as extensively as the autosomal and Y-linked polymorphisms. Therefore, we planned ...
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Article
Spanish population data and forensic usefulness of a novel Y-STR set (DYS437, DYS438, DYS439, DYS460, DYS461, GATA A10, GATA C4, GATA H4)
DNA ty** of 8 recently described STRs on the Y chromosome was carried out by means of 2 multiplex amplification reactions for 134 unrelated males from Cantabria, a region in northern Spain. Multiplex 1 inclu...
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Article
Significance of micro-geographical population structure in forensic cases: a bayesian exploration
We studied the influence of population structure at the microgeographical level on the analysis of forensic cases. A total of nine autosomal STRs and seven Y-STRs were analyzed in the general mixed population ...
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Article
Sequence structure and population data of two X-linked markers: DXS7423 and DXS8377
DXS7423 and DXS8377 are two microsatellite markers located in the q28 band of chromosome X. We developed a protocol to amplify both markers in a single reaction, sequenced the most common alleles and studied ...
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Article
The prosecutor's and defendant's Bayesian nomograms
Two nomograms to calculate posterior odds and probabilities in forensic cases according to Bayes' theorem are presented.
