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PCNA Structure and Interactions with Partner Proteins

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  1. Article

    Open Access

    Structure of the processive human Pol δ holoenzyme

    In eukaryotes, DNA polymerase δ (Pol δ) bound to the proliferating cell nuclear antigen (PCNA) replicates the lagging strand and cooperates with flap endonuclease 1 (FEN1) to process the Okazaki fragments for ...

    Claudia Lancey, Muhammad Tehseen, Vlad-Stefan Raducanu… in Nature Communications (2020)

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  2. Article

    Open Access

    Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation

    Protein-induced fluorescence enhancement (PIFE) is a popular tool for characterizing protein-DNA interactions. PIFE has been explained by an increase in local viscosity due to the presence of the protein resid...

    Fahad Rashid, Vlad-Stefan Raducanu, Manal S. Zaher… in Nature Communications (2019)

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