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Article
Open AccessStructure of the processive human Pol δ holoenzyme
In eukaryotes, DNA polymerase δ (Pol δ) bound to the proliferating cell nuclear antigen (PCNA) replicates the lagging strand and cooperates with flap endonuclease 1 (FEN1) to process the Okazaki fragments for ...
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Open AccessInitial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation
Protein-induced fluorescence enhancement (PIFE) is a popular tool for characterizing protein-DNA interactions. PIFE has been explained by an increase in local viscosity due to the presence of the protein resid...
