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Open AccessPlasma cell-free DNA as a sensitive biomarker for multi-cancer detection and immunotherapy outcomes prediction
Cell-free DNA (cfDNA) has shown promise in detecting various cancers, but the diagnostic performance of cfDNA end motifs for multiple cancer types requires verification. This study aimed to assess the utility ...
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Article
Open AccessCancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma
Besides featured glucose consumption, recent studies reveal that cancer cells might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); however, the underlying mechanisms remai...
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Article
Open AccessCirculating tumor DNA integrating tissue clonality detects minimal residual disease in resectable non-small-cell lung cancer
Circulating tumor DNA (ctDNA) has been proven as a marker for detecting minimal residual diseases following systemic therapies in mid-to-late-stage non-small-cell lung cancers (NSCLCs) by multiple studies. How...