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Article
Open AccessTrkB phosphorylation in serum extracellular vesicles correlates with cognitive function enhanced by ergothioneine in humans
Oral administration of the food-derived antioxidant amino acid ergothioneine (ERGO) results in its efficient distribution in the brain and enhances cognitive function. However, effect of ERGO deficiency on cog...
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Article
Open AccessNatural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Lipid transfer proteins mediate inter-organelle transport of membrane lipids at organelle contact sites in cells, playing fundamental roles in the lipidome and membrane biogenesis in eukaryotes. We previously ...
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Chapter
Novel Intermolecular Surface Force Unveils the Driving Force of the Actomyosin System
In this chapter, we discuss the role of water in actomyosin-force generation. We have been investigating the hydration properties of ions, organic molecules, and proteins. These studies revealed that actin fil...
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Spatial Distribution of Ionic Hydration Energy and Hyper-Mobile Water
In this chapter, we provide the following two topics.
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We carry out DRS measurements for divalent metal chloride and trivalent metal chl...
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Motor Protein Mechanism Coupled with Hydrophobic Hydration/Dehydration Cycle
Muscle protein myosin is one of the most attractive mechanochemical enzymes which convert chemical energy into mechanical work. Figure 13.1 shows a schematic image of actin-myosin interaction producing a slidi...
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Article
Crystal Structure of 7-[(7S)-7-Amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid
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Article
Determination of Benzo [a] pyrene in Airborne Particulates by Automated Thermal Desorption Gas Chromatography