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Article

The p53/p73 - p21^CIP1 tumor suppressor axis guards against chromosomal instability by restraining CDK1 in human cancer cells

Whole chromosome instability (W-CIN) is a hallmark of human cancer and contributes to the evolvement of aneuploidy. W-CIN can be induced by abnormally increased microtubule plus end assembly rates during mitos...

Ann-Kathrin Schmidt, Karoline Pudelko, Jan-Eric Boekenkamp, Katharina Berger… in Oncogene (2021)