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    Profiling Numerical and Structural Chromosomal Instability in Different Cancer Types

    Many cancers display whole chromosome instability (W-CIN) and structural chromosomal instability (S-CIN), referring to increased rates of acquiring numerically and structurally abnormal chromosome changes. Thi...

    **aoxiao Zhang, Maik Kschischo in Cancer Cytogenetics and Cytogenomics (2024)

  2. Article

    Open Access

    Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling

    Whole genome doubling is a frequent event during cancer evolution and shapes the cancer genome due to the occurrence of chromosomal instability. Yet, erroneously arising human tetraploid cells usually do not p...

    Sara Vanessa Bernhard, Katarzyna Seget-Trzensiok, Christian Kuffer… in Cellular Oncology (2022)

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