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Article
Role of albumin in the metabolism and excretion of ochratoxin A
Ochratoxin A (OTA) is known to be strongly bound to serum albumin, but it remains unknown how albumin affects its metabolism and kinetics. To close this gap, we used a mouse model, where heterozygous albumin d...
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Article
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology for which there are no approved therapeutic options. Patients with PSC display changes in gut microbiota and in ...