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    Article

    Role of albumin in the metabolism and excretion of ochratoxin A

    Ochratoxin A (OTA) is known to be strongly bound to serum albumin, but it remains unknown how albumin affects its metabolism and kinetics. To close this gap, we used a mouse model, where heterozygous albumin d...

    Michael Kuhn, Reham Hassan, Daniela González, Maiju Myllys in Mycotoxin Research (2024)

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    Article

    Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling

    Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown aetiology for which there are no approved therapeutic options. Patients with PSC display changes in gut microbiota and in ...

    Kai Markus Schneider, Lena Susanna Candels, Johannes R. Hov in Nature Metabolism (2021)