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Article
Comparing classical and quantum PageRanks
Following recent developments in quantum PageRanking, we present a comparative analysis of discrete-time and continuous-time quantum-walk-based PageRank algorithms. Relative to classical PageRank and to differ...
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Article
Open AccessMorning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial
The cathepsin K inhibitor, ONO-5334, improves bone mineral density in postmenopausal women with osteoporosis. The effects of morning versus evening administration of ONO-5334 were investigated by measuring bon...
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Article
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
The hypoglycaemic actions of metformin have been proposed to be mediated by hepatic AMP-activated protein kinase (AMPK). As the effects of metformin and the role of AMPK in adipose tissue remain poorly charact...
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Article
Open AccessImportance of inhaler-device satisfaction in asthma treatment: Real-world observations of physician-observed compliance and clinical/patient-reported outcomes
It is hypothesized that health and patient-reported outcomes in asthma are positively influenced by the level of patient satisfaction with their inhaler device. This paper uses data from a real-world observati...
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Article
Open AccessThe patient-physician partnership in asthma: Real-world observations associated with clinical and patient-reported outcomes
It is hypothesized that a good partnership between asthma patients and their physicians has a direct and positive influence on the patients’ clinical and patient-reported outcomes. Conversely, poor partnership...
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Article
Genetic divergence among sympatric colour morphs of the Dalmatian wall lizard (Podarcis melisellensis)
If alternative phenotypes in polymorphic populations do not mate randomly, they can be used as model systems to study adaptive diversification and possibly the early stages of sympatric speciation. In this cas...
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Chapter and Conference Paper
Statistical Models for Distributions of Ambient Fine Particulate Matter
This study evaluates the usefulness of structured non-linear regression models for the prediction of annual ambient fine particulate matter (FPM) concentration distributions. The method developed in this study...
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Article
Indications for Fetal Echocardiography
Congenital heart disease is one of the most common congenital malformations diagnosed in liveborns. As more women undergo prenatal diagnosis, the need for screening fetal echocadiography increases. The fetal, ...
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Chapter and Conference Paper
A Proposed Framework for Multinational Comparative Risk Analysis: Pesticide Use, Impacts and Management
Comparative risk assessment is a natural tool for decision making regarding transboundary environmental issues. A workgroup of environmental experts met during the NATO Workshop over three days and addressed t...
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Article
Open AccessClinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent
The antitumour action of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) is mediated through tumour-selective antivascular effects and cytokine induction. This clinical phase I trial was conducted to examine its ...
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Article
Serial studies of evoked potentials and circulating lymphocyte subsets for multiple sclerosis: attempts to monitor progress
A concurrent change in evoked potential measurements and quantitation of circulating T-suppressor (CD8) lymphocyte subpopulations might indicate increased subclinical disease activity. Eight untreated patients...
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Article
Effect of stanozolol on δ-aminolaevulinic acid synthase and hepatic monooxygenase activity in man and rat
Stanozolol is an anabolic steroid which is used in the treatment of aplastic anaemia and has been recently advocated for the prophylaxis of vascular thrombosis. Similar steroid substances stimulate the activit...
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Article
Calculation and evaluation of the gibbs energies of formation of Cr3C2, Cr7C3, and Cr23C6
A thermodynamic analysis of chemical composition data for a series of iron alloys containing chromium and carbon has been completed. These data were obtained from literature compilations for alloys equilibrate...
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Article
Direct Reduction of Iron Ore
In the search for a pure, available iron source, steelmakers are focusing their attention on Directly Reduced Iron (DRI). This material is produced by the reaction of a low gangue iron ore with a hydrocarbonac...