6 Result(s)
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Article
Open AccessMorning vs evening dosing of the cathepsin K inhibitor ONO-5334: effects on bone resorption in postmenopausal women in a randomized, phase 1 trial
The cathepsin K inhibitor, ONO-5334, improves bone mineral density in postmenopausal women with osteoporosis. The effects of morning versus evening administration of ONO-5334 were investigated by measuring bon...
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Article
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
The hypoglycaemic actions of metformin have been proposed to be mediated by hepatic AMP-activated protein kinase (AMPK). As the effects of metformin and the role of AMPK in adipose tissue remain poorly charact...
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Article
Open AccessImportance of inhaler-device satisfaction in asthma treatment: Real-world observations of physician-observed compliance and clinical/patient-reported outcomes
It is hypothesized that health and patient-reported outcomes in asthma are positively influenced by the level of patient satisfaction with their inhaler device. This paper uses data from a real-world observati...
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Article
Open AccessThe patient-physician partnership in asthma: Real-world observations associated with clinical and patient-reported outcomes
It is hypothesized that a good partnership between asthma patients and their physicians has a direct and positive influence on the patients’ clinical and patient-reported outcomes. Conversely, poor partnership...
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Article
Indications for Fetal Echocardiography
Congenital heart disease is one of the most common congenital malformations diagnosed in liveborns. As more women undergo prenatal diagnosis, the need for screening fetal echocadiography increases. The fetal, ...
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Article
Serial studies of evoked potentials and circulating lymphocyte subsets for multiple sclerosis: attempts to monitor progress
A concurrent change in evoked potential measurements and quantitation of circulating T-suppressor (CD8) lymphocyte subpopulations might indicate increased subclinical disease activity. Eight untreated patients...
