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Article
Open AccessIn a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification
Atopic dermatitis is a chronic inflammatory skin disease with defects in the epidermal barrier. In a cohort of African-American children, a FLG2 nonsense mutation has been associated with the disease. In the epid...
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Chapter and Conference Paper
In Search of Beta-Rhizobia: Exploring the Symbionts of Mimosa in Brazil
In 2001, the first identification of β-proteobacteria, which belong to the Burkholderia and Ralstonia genera and are able to nodulate legumes, has changed the long-held perception that legumes can only form nitro...
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Article
Bioactive hydroxyphenylpyrrole-dicarboxylic acids from a new marine Halomonas sp.: production and structure elucidation
The new marine Halomonas sp. strain GWS-BW-H8hM (DSM 17996) was found to produce 3-(4′-hydroxyphenyl)-4-phenylpyrrole-2,5-dicarboxylic acid (HPPD-1) and 3,4-bis(4′-hydroxy- phenyl)pyrrole-2,5-dicarboxylic acid (H...
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Article
Genetic variations of cell wall digestibility related traits in floral stems of Arabidopsis thaliana accessions as a basis for the improvement of the feeding value in maize and forage plants
Floral stems of Arabidopsis thaliana accessions were used as a model system relative to forage plant stems in genetic variation studies of lignin content and cell wall digestibility related traits. Successive inv...
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Article
The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations
Deimination, a post-translational modification catalyzed by peptidylarginine deiminases (PADs), appears as a crucial Ca2+-dependent event in the last steps of epidermal differentiation. In normal human epidermis,...
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Article
Consumption of Dissolved Amino Acids and Carbohydrates by Limnetic Bacterioplankton According to Molecular Weight Fractions and Proportions Bound to Humic Matter
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Article
Density-dependent recruitment after winter disturbance on tidal flats by the lugworm Arenicola marina
The polychaete Arenicola marina is abundant and widespread on intertidal sand flats in Königshafen (island of Sylt, North Sea). Juveniles overwinter in subtidal channels and then colonize the upper tidal zone ab...
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Article
Myofibroblast phenotype and apoptosis in keloid and palmar fibroblasts in vitro
Keloid formation is a wound healing response, which fails to resolve and leads to formation of a raised collagen mass extending beyond the original wound margins. Keloids are typically excluded from palms and ...
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Article
Rig2, a RING finger protein that interacts with the Kin28/Ccl1 CTD kinase in yeast
Kin28/Ccl1, a cyclin-dependent kinase, is essential for the in vivo phosphorylation of the C-terminal domain of the largest subunit of RNA polymerase II in Saccharomyces cerevisiae. In a search for mutations co-...
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Article
Use of dissolved carbohydrates by planktonic bacteria in a mesotrophic lake
Dissolved carbohydrates comprise one of the largest pools of labile organic matter readily available for bacterial use in pelagic ecosystems. Despite this fact, very little is known about use of dissolved carb...
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Article
Growth limitation of planktonic bacteria in a large mesotrophic lake
We studied nutrient-limitation of bacterioplankton growth in Lake Constance, a mesotrophic lake, between February and August in 1992. We amended 1-μm filtrates with a single nutrient or nutrient combinations a...
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Article
The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization
The GUT1 gene of Saccharomyces cerevisiae, encoding glycerol kinase, was cloned and sequenced. The cloned genomic DNA fragment contains an open reading frame potentially coding for a protein of 709 amino acids wi...
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Chapter and Conference Paper
DNA Polymerase δ (POL3) of Saccharomyces cerevisiae
There are three DNA polymerases in yeast which are essential for cell proliferation. Whereas DNA polymerase α (POL1) might be involved in the initiation of nuclear DNA replication (Pizzagalli et al., 1988), the s...
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Chapter
Bacterial Cycling of Matter in the Pelagic Zone of Aquatic Ecosystems
This paper discusses the role of bacteria in influencing the patterns of organic and inorganic matter fluxes in pelagic ecosystems of lakes and oceans. We find that the ecological and biogeochemical roles of b...
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Article
A 20S particle ubiquitous from yeast to human
We have purified and characterized a particle sedimenting at 20S from the postribosomal fraction of yeast, wheat germ,Drosophila melanogaster tissue culture cells, chicken embryo fibroblasts, rabbit reticulocyte ...
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Chapter and Conference Paper
Genetic Control of Bacterial Adhesion
Adhesive substances represent a solution to the problem of colonizing varied surfaces in the bacterial habitat. A given species may have genetic information for a large repertoire of adhesive substances, and t...
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Article
Über den Abbau des d-Histidins beim Meerschweinchen