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  1. Article

    Open Access

    In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

    Atopic dermatitis is a chronic inflammatory skin disease with defects in the epidermal barrier. In a cohort of African-American children, a FLG2 nonsense mutation has been associated with the disease. In the epid...

    V Pendaries, M Le Lamer, L Cau, B Hansmann, J Malaisse, S Kezic in Cell Death & Disease (2015)

  2. No Access

    Chapter and Conference Paper

    In Search of Beta-Rhizobia: Exploring the Symbionts of Mimosa in Brazil

    In 2001, the first identification of β-proteobacteria, which belong to the Burkholderia and Ralstonia genera and are able to nodulate legumes, has changed the long-held perception that legumes can only form nitro...

    C. Bontemps, G. Elliott, E. James, J. Sprent in Biological Nitrogen Fixation: Towards Pove… (2008)

  3. No Access

    Article

    Bioactive hydroxyphenylpyrrole-dicarboxylic acids from a new marine Halomonas sp.: production and structure elucidation

    The new marine Halomonas sp. strain GWS-BW-H8hM (DSM 17996) was found to produce 3-(4′-hydroxyphenyl)-4-phenylpyrrole-2,5-dicarboxylic acid (HPPD-1) and 3,4-bis(4′-hydroxy- phenyl)pyrrole-2,5-dicarboxylic acid (H...

    L. Wang, T. Groβe, H. Stevens, T. Brinkhoff in Applied Microbiology and Biotechnology (2006)

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    Article

    Genetic variations of cell wall digestibility related traits in floral stems of Arabidopsis thaliana accessions as a basis for the improvement of the feeding value in maize and forage plants

    Floral stems of Arabidopsis thaliana accessions were used as a model system relative to forage plant stems in genetic variation studies of lignin content and cell wall digestibility related traits. Successive inv...

    Y. Barrière, D. Denoue, M. Briand, M. Simon, L. Jouanin in Theoretical and Applied Genetics (2006)

  5. No Access

    Article

    The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations

    Deimination, a post-translational modification catalyzed by peptidylarginine deiminases (PADs), appears as a crucial Ca2+-dependent event in the last steps of epidermal differentiation. In normal human epidermis,...

    M. C. Méchin, M. Enji, R. Nachat, S. Chavanas in Cellular and Molecular Life Sciences CMLS (2005)

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    Article

    Consumption of Dissolved Amino Acids and Carbohydrates by Limnetic Bacterioplankton According to Molecular Weight Fractions and Proportions Bound to Humic Matter

    B. Rosenstock, M. Simon in Microbial Ecology (2003)

  7. Article

    Density-dependent recruitment after winter disturbance on tidal flats by the lugworm Arenicola marina

    The polychaete Arenicola marina is abundant and widespread on intertidal sand flats in Königshafen (island of Sylt, North Sea). Juveniles overwinter in subtidal channels and then colonize the upper tidal zone ab...

    K. Reise, M. Simon, E. Herre in Helgoland Marine Research (2001)

  8. Article

    Myofibroblast phenotype and apoptosis in keloid and palmar fibroblasts in vitro

    Keloid formation is a wound healing response, which fails to resolve and leads to formation of a raised collagen mass extending beyond the original wound margins. Keloids are typically excluded from palms and ...

    C C Chipev, R Simman, G Hatch, A E Katz, D M Siegel in Cell Death & Differentiation (2000)

  9. No Access

    Article

    Rig2, a RING finger protein that interacts with the Kin28/Ccl1 CTD kinase in yeast

    Kin28/Ccl1, a cyclin-dependent kinase, is essential for the in vivo phosphorylation of the C-terminal domain of the largest subunit of RNA polymerase II in Saccharomyces cerevisiae. In a search for mutations co-...

    G. Faye, M. Simon, J. G. Valay, D. Fesquet, C. Facca in Molecular and General Genetics MGG (1997)

  10. No Access

    Article

    Use of dissolved carbohydrates by planktonic bacteria in a mesotrophic lake

    Dissolved carbohydrates comprise one of the largest pools of labile organic matter readily available for bacterial use in pelagic ecosystems. Despite this fact, very little is known about use of dissolved carb...

    K. Hanisch, B. Schweitzer, M. Simon in Microbial Ecology (1996)

  11. No Access

    Article

    Growth limitation of planktonic bacteria in a large mesotrophic lake

    We studied nutrient-limitation of bacterioplankton growth in Lake Constance, a mesotrophic lake, between February and August in 1992. We amended 1-μm filtrates with a single nutrient or nutrient combinations a...

    B. Schweitzer, M. Simon in Microbial Ecology (1995)

  12. No Access

    Article

    The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization

    The GUT1 gene of Saccharomyces cerevisiae, encoding glycerol kinase, was cloned and sequenced. The cloned genomic DNA fragment contains an open reading frame potentially coding for a protein of 709 amino acids wi...

    P. Pavlik, M. Simon, T. Schuster, H. Ruis in Current Genetics (1993)

  13. No Access

    Chapter and Conference Paper

    DNA Polymerase δ (POL3) of Saccharomyces cerevisiae

    There are three DNA polymerases in yeast which are essential for cell proliferation. Whereas DNA polymerase α (POL1) might be involved in the initiation of nuclear DNA replication (Pizzagalli et al., 1988), the s...

    G. Faye, F. Fabre, M. Simon, L. Giot in DNA Replication: The Regulatory Mechanisms (1992)

  14. No Access

    Chapter

    Bacterial Cycling of Matter in the Pelagic Zone of Aquatic Ecosystems

    This paper discusses the role of bacteria in influencing the patterns of organic and inorganic matter fluxes in pelagic ecosystems of lakes and oceans. We find that the ecological and biogeochemical roles of b...

    F. Azam, B. C. Cho, D. C. Smith, M. Simon in Large Lakes (1990)

  15. No Access

    Article

    A 20S particle ubiquitous from yeast to human

    We have purified and characterized a particle sedimenting at 20S from the postribosomal fraction of yeast, wheat germ,Drosophila melanogaster tissue culture cells, chicken embryo fibroblasts, rabbit reticulocyte ...

    A. -P. Arrigo, M. Simon, J. -L. Darlix, P. -F. Spahr in Journal of Molecular Evolution (1987)

  16. No Access

    Chapter and Conference Paper

    Genetic Control of Bacterial Adhesion

    Adhesive substances represent a solution to the problem of colonizing varied surfaces in the bacterial habitat. A given species may have genetic information for a large repertoire of adhesive substances, and t...

    M. Silverman, R. Belas, M. Simon in Microbial Adhesion and Aggregation (1984)

  17. No Access

    Article

    Über den Abbau des d-Histidins beim Meerschweinchen

    S. Edlbacher, M. Simon, M. Becker in Naturwissenschaften (1940)