17 Result(s)

Article

Adverse prognostic impact of KIT mutations in childhood CBF-AML: the results of the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05 trial

M Tokumasu, C Murata, A Shimada, K Ohki, Y Hayashi, A M Saito, J Fujimoto… in Leukemia (2015)

Article

Meat consumption in relation to mortality from cardiovascular disease among Japanese men and women

Although high or low (no) meat consumption was associated with elevated or reduced mortality from cardiovascular disease, respectively, few studies have investigated the association between moderate meat consu...

M Nagao, H Iso, K Yamagishi, C Date, A Tamakoshi in European Journal of Clinical Nutrition (2012)

Article

Expression of paraoxonase isoform did not confer protection from acute sarin poisoning in the Tokyo subway terrorist attack

We previously reported the polymorphism of the high density lipoprotein-associated enzyme paraoxonase (PON1), in the 10 sarin poisoning victims in the Tokyo subway terrorist attack. Arg₁₉₂ PON1, which has low sa...

Y. Yamada, T. Takatori, M. Nagao, H. Iwase… in International Journal of Legal Medicine (2001)

Article

Apraxia of speech associated with an infarct in the precentral gyrus of the insula

It has been postulated that the precentral gyrus in the left insula is responsible for co-ordination of speech. We report a paitent with this disturbance who showed an acute infarct limited to this region.

M. Nagao, K. Takeda, T. Komori, E. Isozaki, S. Hirai in Neuroradiology (1999)

Article

Does the sequence of onset of rigor mortis depend on the proportion of muscle fibre types and on intra-muscular glycogen content?

We examined the postmortem changes in the levels of ATP, glycogen and lactic acid in two masticatory muscles and three leg muscles of rats. The proportion of fibre types of the muscles was determined with NIH...

M. Kobayashi, T. Takatori, M. Nakajima, K. Saka… in International Journal of Legal Medicine (1999)

Article

Expressions of four major protein Ser/Thr phosphatases in human primary leukemic cells

Activity and expression of four major protein serine/threonine (Ser/Thr) phosphatases, protein phosphatase type 1 (PP1), protein phosphatase type 2A (PP2A), protein phosphatase type 2B (PP2B) and protein phosp...

M Yamamoto, Y Suzuki, H Kihira, H Miwa, K Kita, M Nagao, S Tamura, H Shiku… in Leukemia (1999)

Article

Expression of phosphotyrosine and SNAP-25 immunoreactivity in grumose (foamy) spheroid bodies suggests axonal regeneration

To investigate the origin of grumose (foamy) spheroid bodies (GFSB), the expression of two proteins associated with axonal regeneration, i.e., phosphotyrosine and 25-kDa synaptosomal-associated protein (SNAP-...

M. Nagao, Shuichi Kato, Masaya Oda, Shunsaku Hirai in Acta Neuropathologica (1998)

Article

Decrease of protein kinase C in the spinal motor neurons of amyotrophic lateral sclerosis

The expression of protein kinase C (PKC), a calcium- and phospholipid-dependent signaling molecule, was studied immunohistochemically in the spinal motor neurons of cases of sporadic amyotrophic lateral scler...

M. Nagao, Shuichi Kato, Masaya Oda, Shunsaku Hirai in Acta Neuropathologica (1998)

Chapter and Conference Paper

Hyperthermo-Chemo-Hypoxic Isolated Liver Perfusion for Hepatic Metastases: A Possible Adjuvant Approach

As a possible intraoperative adjuvant approach to treating hepatic metastases we developed a method of hyperthermo-chemo-hypoxic isolated liver perfusion in combination with hepatic resection. This method was ...

Y. Nakajima, M. Horikawa, T. Kin, T. Ohyama… in Isolated Liver Perfusion for Hepatic Tumors (1998)

Article

Postmortem MRI of the spinal cord in multiple sclerosis

Postmortem magnetic resonance imaging (MRI) of the spinal cord and the brainstem in a patient with multiple sclerosis are compared with the histopathological findings. Abnormal high signal intensity areas on T...

M. Nagao, M. Ogawa, H. Yamauchi in Neuroradiology (1994)

Article

Haemorrhage in the inferior colliculus

M. Nagao, Y. Kita, H. Kamo in Neuroradiology (1992)

Chapter and Conference Paper

Lipoprotein (A) (LP(A)): Its Relevance to Diabetic Angiopathy

Lipoprotein(a)(Lp(a)) was first discovered by Berg as a low-density lipoprotein like molecule in 1963. Much of the interest in the Lp(a) stems from several clinical studies that showed a highly significant ass...

T. Taminato, F.-N. Hu, T. Tominaga, S. Sen, T. Yoshimi… in Hemostasis and Circulation (1992)

Article

A comparative study of diazepam levels in bone marrow versus serum, saliva and brain tissue

The distribution of diazepam in biological fluids and tissues of rats was examined 1, 2, 4 and 8 h after intraperitoneal administration by using a radioimmunoassay with specific anti-diazepam antibody. The dia...

T. Takatori, S. Tomii, K. Terazawa, M. Nagao… in International Journal of Legal Medicine (1991)

Chapter and Conference Paper

Risk Assessment of Naturally Occurring Carcinogens

In 1976, a big symposium was held at the Cold Spring Harbor Laboratory, and the papers presented at that time were published as a three-volume book entitled “Origins of Human Cancer” (Cold Spring Harbor Labora...

T. Sugimura, M. Nagao, K. Wakabayashi in Risk Assessment in Chemical Carcinogenesis (1991)

Article

A case of carbamylphosphate synthetase-I deficiency associated with secondary carnitine deficiency —l-carnitine treatment of CPS-I deficiency

We describe a male infant with congenital hyperammonaemia due to partial carbamylphosphate synthetase-I (CPS-I) deficiency. At 21 days of age, he had convulsions and at 53 days of age hyperammonaemic coma. The...

T. Mori, A. Tsuchiyama, K. Nagai, M. Nagao, K. Oyanagi… in European Journal of Pediatrics (1990)

Chapter and Conference Paper

Factors Modulating Mutagenicity in Microbial Tests

The preincubation of test compound, bacterial tester strain, and S-9 mix or buffer before pouring a minimal-glucose agar plate enhanced the sensitivity of mutation test and increased the spectrum of mutagens d...

T. Matsushima, T. Sugimura, M. Nagao… in Short-Term Test Systems for Detecting Carc… (1980)