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Open AccessWhich aspects of health care are most valued by people living with HIV in high-income countries? A systematic review
Increasing numbers of people with HIV are living into older age and experiencing comorbidities. The development of new models of care to meet the needs of this population is now a priority. It is important tha...
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LDL from obese patients with the metabolic syndrome show increased lipid peroxidation and activate platelets
This study assessed oxidative stress in LDL from obese patients with the metabolic syndrome and compared it with that in LDL from type 2 diabetic patients or control volunteers. It also determined the effect o...
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Open AccessDHA Metabolism: Targeting the Brain and Lipoxygenation
Docosahexaenoic acid (DHA), the end-product of the metabolism of omega-3 family fatty acids, is the main polyunsaturated fatty acid of the brain, but its accumulation is incompletely understood. This paper rev...
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Proprioception and Imitation: On the Road to Agent Individuation
In this paper, we will show that different kinds of interactive behaviors can emerge according to the kind of proprioceptive function available in a given sensori-motor system. We will study three different ex...
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Lipid sensing and lipid sensors
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Effect of glycated LDL on microvascular tone in mice: a comparative study with LDL modified in vitro or isolated from diabetic patients
In vitro studies have suggested that glycation of LDL might be implicated in diabetic microangiopathy. We therefore investigated the in vivo effects of LDL glycated in vitro on the mouse skeletal muscle arteri...
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Pathophysiologic role of redox status in blood platelet activation. Influence of docosahexaenoic acid
Decrease of platelet glutathione peroxidase activity results in increased life span of lipid hydroperoxides, especially the 12-lipoxygenase product of arachidonic acid, 12-HpETE. Phospholipase A2 activity is subs...
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Article
Brief preconditioning ischemia alters diacylglycerol content and composition in rabbit heart
In order to give further insight into the potential role of PKC in beneficial effects of ischemic preconditioning, we have characterized the production of diacylglycerol, the endogenous activator of PKC, and ...
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Article
Synthesis of acetyl, docosahexaenoyl-glycerophosphocholine and its characterization using nuclear magnetic resonance
Docosahexaenoic acid (DHA) circulates in mammals in lipoproteins and bound to serum albumin as a nonesterified fatty acid as well as esterified in lysophosphatidylcholine (lysoPC). 1-Lyso,2-DHA-glycerophosphoc...
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35th Annual Meeting of the European Association for the Study of Diabetes
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Very low dietary intake of n-3 fatty acids affects the immune function of healthy elderly people
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Regulation of cAMP-phosphodiesterases by phosphatidic acid binding
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Opposite regulation of prostaglandin H synthase isoforms by eicosapentaenoic and docosahexaenoic acids
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Biological Relevance of the 12-Lipoxygenase Pathway for Platelet and Lymphocyte Functions
The 12-lipoxygenase activity has been the first animal lipoxygenase activity reported; it was discovered during the study of the oxygenation of arachidonic acid by blood platelets (1,2). It produces 12(S)-hydrope...
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Inhibition of Ca2+-independent phospholipase A2 affects arachidonate-, not docosahexaenoate-, phospholipid remodeling in UIII cells
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Phosphatidic acid-dependent activation of adenosine-3′,5′-cyclic-monophosphate-phosphodiesterase is necessary for arg-vasopressin induction of myogenesis
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Hyperglycaemia modifies the reaction of microvessels to insulin in rat skeletal muscle
The role played by glucose and/or insulin in local vascular regulation of tissue glucose uptake is largely unknown. Thus, the aim of this study was to examine microvascular changes induced either by hyperinsu...
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N-3 Fatty Acids. Antithromboxane Activity. Effects on Redox Status of Blood Cells
N-3 fatty acids are polyunsaturated ones that all derive from linolenic acid (18:3n-3) in animals. Together with linoleic acid (18:2n-6), that cannot be synthesized in animals, 18:3n-3 is considered as an esse...
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Phospholipid molecular species from human placenta lipids
The phospholipid molecular species from a large-scale preparation of human placenta lipids were analyzed. The major placental phospholipids were choline glycerophospholipids (CPL) (53.2 wt%), sphingomyelin (21...
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Article
Holes photogeneration in phthalocyanine-doped polysilane
Polysilane polymers are attractive photoconductive materials, due to the high mobility of the charge carriers (holes). The photoconductivity in the visible region is greatly enhanced by the addition of a phtha...