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Open AccessClass, race and ethnicity and information avoidance among cancer survivors
Information seeking may increase cancer survivors’ ability to make decisions and cope with the disease, but many also avoid cancer information after diagnosis. The social determinants and subsequent communicat...
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Combining radiation therapy with interstitial radiation-inducible TNF-α expression for locoregional cancer treatment
Brachytherapy (BRT) is used in the treatment of human cancers, including the cervix, breast, prostate and head and neck cancers. The primary advantage of BRT lies in the spatial conformation of the radiation d...
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Open AccessR306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies
R306465 is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models. R306465 was found to be a ...
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Article
Open AccessMethylation status of p14ARF and p16INK4a as detected in pancreatic secretions
The clinical management of pancreatic disease is often hampered by a lack of tissue diagnosis. Endoscopic pancreatography offers the opportunity to investigate exfoliated cells. However, the significance of me...
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Open AccessMethods in molecular biology: minor errors in primer citations with major consequences: how can we minimize these mistakes?
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Fas ligand gene-carrying adeno-5 AdEasy viruses can be efficiently propagated in apoptosis-sensitive human embryonic retinoblast 911 cells
Recent reports have pointed out the difficulties in generating recombinant adenoviral vectors expressing FasL using eukaryotic cells. In the present study we cloned the murine FasL (mFasL) gene into the pCA14 ...
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Dysmyelination In Mice and the Proteolipid Protein Gene Family
Myelin is a cellular specialization of vertebrate neuroglia which provides the physical basis for rapid impulse conduction: by electrically insulating axonal segments, myelin sheaths restrict action potentials...
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Absence of interaction between tenoxicam and warfarin
The influence of tenoxicam on plasma warfarin concentrations and on its anticoagulant effect has been studied in healthy volunteers. Tenoxicam did not alter the plasma warfarin concentration versus time profil...
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Article
Pharmacological characterization of the physostigmine stimulus in rats
Rats were trained to discriminate 0.10 mg/kg SC physostigmine from saline in a two-lever food-reinforced task. There was generalization to the acetylcholine esterase inhibitor THA as well as to the muscarinic ...
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Hypothermia in Hodgkin's disease after exploratory laparotomy
Hypothermia is a rare complication of unknown origin in Hodgkin's disease which has been reported after the administration of antineoplastic agents, chlorpromazine and paracetamol. We report a highly febrile p...
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Characterization of the scopolamine stimulus in rats
The discriminative stimulus properties of scopolamine, a potent antagonist at muscarinic receptors, were used for testing the discriminative effects of drugs known to act on cholinergic transmission. Rats were...
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Hämorheologie und Akute Phase Reaktion nach Thrombendarteriektomie der extracraniellen Arteria carotis
In 39 patients with hemodynamically significant stenoses of the internal carotid artery thrombendarterectomy was performed. Hemorheological properties and plasma protein levels were studied pre- and postoperat...
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Discriminative stimulus properties of muscarinic agonists
In a two-lever, food-reinforced drug-discrimination paradigm separate groups of rats were trained to discriminate either arecoline, pilocarpine or oxotremorine from saline. The discriminative cues of all three...
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Evidence of chronic persistent infections with polyomaviruses (BK type) in renal transplant recipients
Ten renal transplant recipients showing a significant increase in human polyomavirus antibodies, indicative of an acute infection, were followed up serologically over periods ranging from two months to more th...
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Epidemiologie, Virologie und virologische Diagnose der Cytomegalie
Infections with cytomegalovirus are common in all parts of the world. The virus may persist for many years in presence of high serum-antibody levels and infections may be transmitted by antibody-carriers. The ...
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Article
Antigenic relationship between human cytomegalovirus. Herpes simplex, and Varieella-Zoster virus studied by complement-fixation
The antigenic relationship between CMV, HSV, and VZV viruses was studied by the complement-fixation. 47 sera from congenitally infected children excreting CMV regularly possessed homologous antibodies, mostly ...
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The development of neutralizing antibodies in guinea pigs following immunization with human Cytomegalovirus
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