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  1. Article

    Open Access

    Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions

    Malic enzyme 1 (ME1) regulates one of the main pathways that provide nicotinamide adenine dinucleotide phosphate (NADPH), which is essential for cancer cell growth through maintenance of redox balance and bios...

    S Murai, A Ando, S Ebara, M Hirayama, Y Satomi, T Hara in Oncogenesis (2017)

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