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Article

Proton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance

Incidence of sepsis is increasing, representing a tremendous burden for health-care systems. Death in acute sepsis is attributed to hyperinflammatory responses, but the underlying mechanisms are still unclear....

E Balza, P Piccioli, S Carta, R Lavieri, M Gattorno, C Semino… in Cell Death & Disease (2016)