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Mutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System
Hyperactivity of central neuropeptidergic circuits such as the corticotropin-releasing hormone (CRH) and vasopressin (AVP) neuronal systems is thought to play a causal role in the etiology and symptomatology o...
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Chapter
Challenge Studies in Anxiety Disorders
In psychiatry, the use of pharmacological challenges in panic disorder is unique in that the clinical phenomenon of central interest (i.e., the panic attack) can be provoked readily and assessed in the clinica...