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Article
Repetitive Transcranial Magnetic Stimulation Increases the Release of Dopamine in the Nucleus Accumbens Shell of Morphine-Sensitized Rats During Abstinence
Recent studies in rodents have shown that withdrawal from chronic drug abuse is associated with a significant decrease in dopamine (DA) release in mesolimbic structures, especially in the shell region of the n...
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Chapter
Mutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System
Hyperactivity of central neuropeptidergic circuits such as the corticotropin-releasing hormone (CRH) and vasopressin (AVP) neuronal systems is thought to play a causal role in the etiology and symptomatology o...
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Chapter
Challenge Studies in Anxiety Disorders
In psychiatry, the use of pharmacological challenges in panic disorder is unique in that the clinical phenomenon of central interest (i.e., the panic attack) can be provoked readily and assessed in the clinica...
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Article
Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks
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Article
Open AccessThe GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders
Recent evidence suggests that the GABA transporter 1 (GAT-1; SLC6A1) plays a role in the pathophysiology and treatment of anxiety disorders. In order to understand the impact of genetic variation within SLC6A1...
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Article
TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies
The lifetime prevalence of panic disorder (PD) is up to 4% worldwide and there is substantial evidence that genetic factors contribute to the development of PD. Single-nucleotide polymorphisms (SNPs) in TMEM13...