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    Chapter

    Mutagenesis and Knockout Models: Hypothalamic-Pituitary-Adrenocortical System

    Hyperactivity of central neuropeptidergic circuits such as the corticotropin-releasing hormone (CRH) and vasopressin (AVP) neuronal systems is thought to play a causal role in the etiology and symptomatology o...

    M.E. Keck, M.B. Müller in Anxiety and Anxiolytic Drugs (2005)

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    Chapter

    Challenge Studies in Anxiety Disorders

    In psychiatry, the use of pharmacological challenges in panic disorder is unique in that the clinical phenomenon of central interest (i.e., the panic attack) can be provoked readily and assessed in the clinica...

    M.E. Keck, A. Ströhle in Anxiety and Anxiolytic Drugs (2005)