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  1. No Access

    Article

    Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety

    The lateral division of the bed nucleus of the stria terminalis (BNST), which forms part of the circuitry regulating fear and anxiety, contains a large number of neurons expressing corticotropin releasing fact...

    K S Sink, D L Walker, S M Freeman, E I Flandreau, K J Ressler… in Molecular Psychiatry (2013)

  2. No Access

    Article

    Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes

    An increase in corticotropin-releasing factor (CRF) is a putative factor in the pathophysiology of stress-related disorders. As CRF expression in the central nucleus of the amygdala (CeA) is important in adapt...

    E Keen-Rhinehart, V Michopoulos, D J Toufexis, E I Martin, H Nair… in Molecular Psychiatry (2009)

  3. No Access

    Article

    Mechanisms of fear extinction

    Excessive fear and anxiety are hallmarks of a variety of disabling anxiety disorders that affect millions of people throughout the world. Hence, a greater understanding of the brain mechanisms involved in the ...

    K M Myers, M Davis in Molecular Psychiatry (2007)

  4. No Access

    Chapter

    Sublexical and Lexical Processing of Young Adults with Learning Disabilities and Attention Deficit/Hyperactivity Disorder

    The purpose of this research was to investigate the performance of three groups of English-speaking university students with disabilities, which included: (a) 93 with learning disabilities (LD); (b) 64 with at...

    N. Gregg, C. Coleman, R. Stennett, M. Davis… in Basic Functions of Language, Reading and R… (2002)

  5. No Access

    Article

    Summary of a National Institute of Mental Health workshop: develo** animal models of anxiety disorders

    Rationale: There exists a wide range of animal models and measures designed to assess anxiety or fearfulness. However, the relationship between these models and clinical anxiety symptoms and syndromes is unclear...

    A. Shekhar, U. McCann, M. Meaney, D. Blanchard, M. Davis, K. Frey… in Psychopharmacology (2001)

  6. No Access

    Article

    The amygdala: vigilance and emotion

    Here we provide a review of the animal and human literature concerning the role of the amygdala in fear conditioning, considering its potential influence over autonomic and hormonal changes, motor behavior and...

    M Davis, P J Whalen in Molecular Psychiatry (2001)

  7. Article

    Relative changes in blood flow with functional electrical stimulation during exercise of the paralyzed lower limbs

    Eight spinal cord injured (SCI) patients performed three sets of exercise with two conditions, 60% and 80% of VO2peak, with an arm crank ergometer. Functional neuromus-cular stimulation was used to induce static ...

    W Phillips, L N Burkett, R Munro, M Davis, K Pomeroy in Spinal Cord (1995)

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  8. No Access

    Article

    Yohimbine facilitated acoustic startle in combat veterans with post-traumatic stress disorder

    Preclinical and clinical studies have suggested that the acoustic startle reflex (ASR) is a useful model to investigate the neurochemical basis of anxiety and fear states. This work has revealed that the anxio...

    C. A. Morgan III, C. Grillon, S. M. Southwick, L. M. Nagy, M. Davis… in Psychopharmacology (1995)

  9. No Access

    Article

    Prepulse inhibition of the acoustic startle reflex using visual and auditory prepulses: disruption by apomorphine

    The amplitude of the acoustic startle reflex can be reduced reliably when preceded at short intervals by a weak stimulus (prepulse) which itself does not elicit startle. The magnitude of this prepulse inhibiti...

    S. Campeau, M. Davis in Psychopharmacology (1995)

  10. No Access

    Article

    Yohimbine — facilitated acoustic startle reflex in humans

    Preclinical studies have suggested the acoustic startle reflex (ASR) may be a useful animal model to investigate the neurochemical basis of anxiety and fear states. This work has revealed that the anxiogenic a...

    C. A. Morgan III, S. M. Southwick, C. Grillon, M. Davis… in Psychopharmacology (1993)

  11. No Access

    Article

    Anxiolytic effects of buspirone and gepirone in the fear-potentiated startle paradigm

    Fear potentiation of the acoustic startle reflex was produced by eliciting startle responses in the presence of a light that had been previously paired with a shock. Buspirone (0.6–5.0 mg/kg) and gepirone (1.2...

    J. H. Kehne, J. V. Cassella, M. Davis in Psychopharmacology (1988)

  12. No Access

    Article

    Serotonin does not mediate anxiolytic effects of buspirone in the fear-potentiated startle paradigm: comparison with 8-OH-DPAT and ipsapirone

    The present study evaluated the role of various neurotransmitter systems in mediating buspirone's blockade of the fear-potentiated startle effect, where acoustic startle amplitude is normally increased in the ...

    M. Davis, J. V. Cassella, J. H. Kehne in Psychopharmacology (1988)

  13. No Access

    Article

    Mescaline: excitatory effects on acoustic startle are blocked by serotonin2 antagonists

    The ability of serotonin2 (5-HT2) antagonists to block the excitatory effects of mescaline on the acoustic startle reflex were analyzed. Mescaline (20 mg/kg) caused a consistent increase in the amplitude of the a...

    M. Davis in Psychopharmacology (1987)

  14. No Access

    Article

    Recurrent inhibition: Its influence upon transduction and afferent discharges in slowly-adapting stretch receptor organs

    The crayfish stretch receptor organs provide the opportunity to study recurrent inhibition (RI) in pure experimental conditions. The slowly adapting organ (SAO) from the cephalothoraxabdomen joint of Procambar...

    J. F. Vibert, M. Davis, J. P. Segundo in Biological Cybernetics (1979)