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5 Result(s)

within M S Choi Remove this filter Health Promotion and Disease Prevention Remove this filter Internal Medicine Remove this filter Metabolic Diseases Remove this filter

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  1. No Access

    Article

    The metabolic response to a high-fat diet reveals obesity-prone and -resistant phenotypes in mice with distinct mRNA-seq transcriptome profiles

    The aim of this study was to explore the phenotypic differences underpinning obesity susceptibility or resistance based on the metabolic and transcriptional profiling of C57BL/6J mice fed a high-fat diet (HFD).

    J-Y Choi, R A McGregor, E-Y Kwon, Y J Kim, Y Han… in International Journal of Obesity (2016)

  2. No Access

    Article

    Integrative systems analysis of diet-induced obesity identified a critical transition in the transcriptomes of the murine liver and epididymal white adipose tissue

    It is well known that high-fat diet (HFD) can cause immune system-related pathological alterations after a significant body weight gain. The mechanisms of the delayed pathological alterations during the develo...

    J Kim, E-Y Kwon, S Park, J-R Kim, S-w Choi, M-S Choi… in International Journal of Obesity (2016)

  3. No Access

    Article

    Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats

    Galectin 1 (GAL1), an animal lectin is well characterized in the context of cancer, tumor environment, but its physiological roles in obesity remain to be demonstrated. In this study, we investigated whether t...

    R Mukherjee, S W Kim, T Park, M S Choi, J W Yun in International Journal of Obesity (2015)

  4. No Access

    Article

    Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters

    4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and prom...

    T H Tu, C-S Kim, J-H Kang, I S Nam-Goong, C W Nam… in International Journal of Obesity (2014)

  5. No Access

    Article

    Time-course microarrays reveal modulation of developmental, lipid metabolism and immune gene networks in intrascapular brown adipose tissue during the development of diet-induced obesity

    The aim of this study was to establish the time-course of molecular events in intrascapular brown adipose tissue (iBAT) during the development of diet-induced obesity using microarrays and molecular network an...

    R A McGregor, E-Y Kwon, S-K Shin, U J Jung, E Kim… in International Journal of Obesity (2013)