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6 Result(s)

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  1. No Access

    Article

    Time-course microarrays reveal modulation of developmental, lipid metabolism and immune gene networks in intrascapular brown adipose tissue during the development of diet-induced obesity

    The aim of this study was to establish the time-course of molecular events in intrascapular brown adipose tissue (iBAT) during the development of diet-induced obesity using microarrays and molecular network an...

    R A McGregor, E-Y Kwon, S-K Shin, U J Jung, E Kim… in International Journal of Obesity (2013)

  2. No Access

    Article

    Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters

    4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and prom...

    T H Tu, C-S Kim, J-H Kang, I S Nam-Goong, C W Nam… in International Journal of Obesity (2014)

  3. No Access

    Article

    Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats

    Galectin 1 (GAL1), an animal lectin is well characterized in the context of cancer, tumor environment, but its physiological roles in obesity remain to be demonstrated. In this study, we investigated whether t...

    R Mukherjee, S W Kim, T Park, M S Choi, J W Yun in International Journal of Obesity (2015)

  4. No Access

    Article

    Integrative systems analysis of diet-induced obesity identified a critical transition in the transcriptomes of the murine liver and epididymal white adipose tissue

    It is well known that high-fat diet (HFD) can cause immune system-related pathological alterations after a significant body weight gain. The mechanisms of the delayed pathological alterations during the develo...

    J Kim, E-Y Kwon, S Park, J-R Kim, S-w Choi, M-S Choi… in International Journal of Obesity (2016)

  5. No Access

    Article

    The metabolic response to a high-fat diet reveals obesity-prone and -resistant phenotypes in mice with distinct mRNA-seq transcriptome profiles

    The aim of this study was to explore the phenotypic differences underpinning obesity susceptibility or resistance based on the metabolic and transcriptional profiling of C57BL/6J mice fed a high-fat diet (HFD).

    J-Y Choi, R A McGregor, E-Y Kwon, Y J Kim, Y Han… in International Journal of Obesity (2016)

  6. No Access

    Article

    Metabolic syndrome is not an independent risk factor for hearing impairment

    We aimed to investigate the association between metabolic syndrome (MS) and hearing impairment (HI) using nationally representative data from Korean adults.

    Ho Yun Lee, Y. J. Choi, H. J. Choi, M. S. Choi… in The journal of nutrition, health & aging (2016)