![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Positive regulation of β-catenin–PROX1 signaling axis by DBC1 in colon cancer progression
Aberrant activation of Wnt/β-catenin pathway contributes to colorectal cancer (CRC) progression. However, little is known about regulatory mechanisms of the β-catenin activity in cancer progression. Here we in...
-
Article
Open AccessSUMOylation of ZFP282 potentiates its positive effect on estrogen signaling in breast tumorigenesis
Estrogen receptor α (ERα) has critical roles in the development and progression of breast cancer, and the coiled-coil co-activator (CoCoA) is an important ERα co-activator for estrogen-induced gene expression....
-
Article
Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription
Linker histone H1.2 has been shown to suppress p53-dependent transcription through the modulation of chromatin remodeling; however, little is known about the mechanisms governing the antagonistic effects of H1...