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within M J Kang Remove this filter Human Genetics Remove this filter

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  1. No Access

    Article

    Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses

    XIAP-associated factor 1 (XAF1) is a new candidate tumor suppressor, which has been known to exert proapoptotic effects by interfering with the caspase-inhibiting activity of XIAP. To explore the XAF1's candid...

    M-G Lee, J-S Huh, S-K Chung, J-H Lee, D-S Byun, B-K Ryu, M-J Kang, K-S Chae… in Oncogene (2006)

  2. No Access

    Article

    Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions

    Transforming growth factor (TGF)-β1 has biphasic functions in prostate tumorigenesis, having a growth-inhibitory effect in the early stages, but in the late stages promoting tumor angiogenesis and metastasis. ...

    K S Chae, M J Kang, J H Lee, B K Ryu, M G Lee, N G Her, T K Ha, J Han, Y K Kim… in Oncogene (2011)

  3. No Access

    Article

    p21-Activated kinase 4 promotes prostate cancer progression through CREB

    Prostate cancer is initially androgen-dependent but, over time, usually develops hormone- and chemo-resistance. The present study investigated a role for p21-activated kinase 4 (PAK4) in prostate cancer progre...

    M-H Park, H-S Lee, C-S Lee, S T You, D-J Kim, B-H Park, M J Kang, W D Heo… in Oncogene (2013)