3 Result(s)
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M J Kang
Life Sciences
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Article
ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21WAF1
ZNF313 encoding a zinc-binding protein is located at chromosome 20q13.13, which exhibits a frequent genomic amplification in multiple human cancers. However, the biological function of ZNF313 remains largely u...
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Article
Open AccessCrucial role of calbindin-D28k in the pathogenesis of Alzheimer’s disease mouse model
Calbindin-D28k (CB), one of the major calcium-binding and buffering proteins, has a critical role in preventing a neuronal death as well as maintaining calcium homeostasis. Although marked reductions of CB expres...
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Article
Open AccessRetrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics
Alveolar epithelial type II (AETII) cells are important for lung epithelium maintenance and function. We demonstrate that AETII cells from mouse lungs exposed to cigarette smoke (CS) increase the levels of the...
