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Article
Pre-menopausal breast cancer and aromatase inhibitors: treating a new generation of women
Aromatase inhibitors have revolutionized the treatment of post-menopausal women with hormone receptor positive breast cancer. However, approximately 22% of all cases of breast cancer in North America are diagn...
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Article
Open AccessHeterogeneity of O6-alkylguanine DNA-alkyltransferase expression in human breast tumours
An important determinant of cellular resistance to chemotherapeutic O6-alkylating agents, which comprise methylating and chloroethylating agents, is the ability of cells to repair alkylation damage at the O6-posi...