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  1. No Access

    Article

    Adolescent polycystic ovary syndrome without obesity: HOTAIR rs1443512 genotype relates to fat mass and to the redistribution of fat mass on low-dose pioglitazone

    Adolescent polycystic ovary syndrome (PCOS) is characterized by androgen excess and oligo-amenorrhea, and often results from ectopic lipid storage due to a mismatch between early adipogenesis and later lipogen...

    F. de Zegher, M. Díaz, L. Ibáñez in Journal of Endocrinological Investigation (2024)

  2. No Access

    Article

    GLP-1 and IGF-I levels are elevated in late infancy in low birth weight infants, independently of GLP-1 receptor polymorphisms and neonatal nutrition

    Low birth weight followed by rapid postnatal weight gain is associated with increased risks for obesity and diabetes in adulthood. Modulation of glucagon-like-peptide 1 (GLP-1) secretion by (epi)genetic mechan...

    M Díaz, C García-Beltran, A López-Bermejo, F de Zegher… in International Journal of Obesity (2018)

  3. No Access

    Article

    Liver volume and hepatic adiposity in childhood: relations to body growth and visceral fat

    The sequence of prenatal growth restraint and postnatal catch-up growth may lead to hepato-visceral adiposity, insulin resistance and low-grade inflammation before the onset of puberty. In prepubertal children...

    R Malpique, J Bassols, A López-Bermejo, M Diaz… in International Journal of Obesity (2018)

  4. No Access

    Article

    Circulating GLP-1 in infants born small-for-gestational-age: breast-feeding versus formula-feeding

    Prenatal growth restraint associates with the risk for later diabetes, particularly if such restraint is followed by postnatal formula-feeding (FOF) rather than breast-feeding (BRF). Circulating incretins can ...

    M Díaz, J Bassols, G Sebastiani, A López-Bermejo… in International Journal of Obesity (2015)

  5. No Access

    Article

    Circulating FGF19 and FGF21 surge in early infancy from infra- to supra-adult concentrations

    Fibroblast growth factor 19 (FGF19) and 21 (FGF21) have been linked to obesity and type 2 diabetes in adults. We assessed the circulating concentrations of these factors in human neonates and infants, and thei...

    D Sánchez-Infantes, J M Gallego-Escuredo, M Díaz… in International Journal of Obesity (2015)

  6. No Access

    Article

    Placental FTO expression relates to fetal growth

    The fat mass and obesity-associated gene (FTO) participates in the control of postnatal weight gain. We assessed whether FTO is expressed in human placenta and whether such expression relates to prenatal weight g...

    J Bassols, A Prats-Puig, M Vázquez-Ruíz… in International Journal of Obesity (2010)

  7. No Access

    Article

    Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease

    Cut points for defining obesity have been derived from mortality data among Whites from Europe and the United States and their accuracy to screen for high risk of coronary heart disease (CHD) in other ethnic g...

    V M Herrera, J P Casas, J J Miranda, P Perel… in International Journal of Obesity (2009)

  8. No Access

    Article

    Milky-white pleural effusion complicating peripherically inserted central venous catheter for total parenteral nutrition

    Pleural effusion secondary to vascular perforation and leakage of total parenteral nutrition (TPN) is a rare complication of central lines. We report such a case and urge physicians to familiarize with recogni...

    M Díaz, I Lorda, C Sánchez, I Gutierrez… in European Journal of Clinical Nutrition (2005)