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  1. No Access

    Article

    The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma

    Aberrant signaling via G protein-coupled receptors (GPCRs) is implicated in numerous diseases including colon cancer. The heterotrimeric G proteins transduce signals from GPCRs to various effectors. So far, th...

    D Fuchs, M Metzig, M Bickeböller, C Brandel, W Roth in Oncogene (2015)

  2. No Access

    Article

    Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival

    The myristoylated alanine-rich C-kinase substrate (MARCKS) acts as a tumor suppressor in a variety of human neoplasms. In colorectal cancers (CRCs), MARCKS has been shown to be a preferential target of mutatio...

    M Bickeböller, K E Tagscherer, M Kloor, L Jansen, J Chang-Claude, H Brenner… in Oncogene (2015)