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within Lukasz A. Joachimiak Remove this filter English Remove this filter Biological Microscopy Remove this filter

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  1. No Access

    Article

    xTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometry

    Chemical cross-linking in combination with mass spectrometry generates distance restraints of amino acid pairs in close proximity on the surface of native proteins and protein complexes. In this study we used ...

    Thomas Walzthoeni, Lukasz A Joachimiak, George Rosenberger, Hannes L Röst… in Nature Methods (2015)

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    Article

    Computational redesign of protein-protein interaction specificity

    We developed a 'computational second-site suppressor' strategy to redesign specificity at a protein-protein interface and applied it to create new specifically interacting DNase-inhibitor protein pairs. We dem...

    Tanja Kortemme, Lukasz A Joachimiak… in Nature Structural & Molecular Biology (2004)