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Clinical and genetic analysis of an Italian family with Machado-Joseph disease

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  1. Article

    Open Access

    Accuracy of the clinical diagnosis of dementia with Lewy bodies (DLB) among the Italian Dementia Centers: a study by the Italian DLB study group (DLB-SINdem)

    Dementia with Lewy bodies (DLB) may represent a diagnostic challenge, since its clinical picture overlaps with other dementia. Two toolkits have been developed to aid the clinician to diagnose DLB: the Lewy Bo...

    Mirella Russo, Claudia Carrarini, Angelo Di Iorio in Neurological Sciences (2022)

  2. Article

    Open Access

    Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington’s and Parkinson’s disease

    Proenkephalin (PENK) and prodynorphin (PDYN) are peptides mainly produced by the striatal medium spiny projection neurons (MSNs) under dopaminergic signaling. Therefore, they may represent candidate biomarkers...

    Peggy Barschke, Samir Abu-Rumeileh, M. H. D. Rami Al Shweiki in Journal of Neurology (2022)

  3. Article

    Open Access

    Redefinition of dementia care in Italy in the era of amyloid-lowering agents for the treatment of Alzheimer’s disease: an expert opinion and practical guideline

    No disease-modifying therapies are currently available for Alzheimer’s disease (AD) in Europe. Current evidence from clinical trials testing anti-beta amyloid (Aβ) monoclonal antibodies (mAbs) in patients with...

    Massimo Filippi, Giordano Cecchetti, Annachiara Cagnin in Journal of Neurology (2023)