3 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Lorenza Spagnuolo
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Article
Open AccessTracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections
Repeated cycles of infections, caused mainly by Pseudomonas aeruginosa, combined with a robust host immune response and tissue injury, determine the course and outcome of cystic fibrosis (CF) lung disease. As the...
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Article
Open AccessIL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa
Resistance and tolerance mechanisms participate to the interplay between host and pathogens. IL-17-mediated response has been shown to be crucial for host resistance to respiratory infections, whereas its role...
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Article
Open AccessThe host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection
Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes likely influenced by genetic backgrounds. Here, we investigated the cellular events involved in resistance and susceptibili...
